FRINK Linked Data Fragments server

Matches in SemOpenAlex for { <https://semopenalex.org/work/W2059633974> ?p ?o ?g. }

• W2059633974 endingPage "61" @default.
• W2059633974 startingPage "53" @default.
• W2059633974 abstract "► We investigated oxidative signaling induced by exposure to excess Cd or Cu. ► Arabidopsis thaliana plants were exposed to environmentally realistic concentrations. ► Cu exposure leads to immediate effects on plant level, Cd effects were delayed. ► Cd and Cu induce specific ROS and MAPK signaling cascades. ► This is due to different chemical properties and/or perception of these metals. Metals, like cadmium (Cd) and copper (Cu), have the ability to induce the production of reactive oxygen species (ROS) at the cellular level. It is widely known that these ROS can cause irreversible damage to cellular components, like DNA, proteins and lipids. On the other hand, ROS can also act as signaling molecules and in this way they play an essential role in many normal physiological processes, but also in defense responses against stress. ROS signaling in plants uses mitogen-activated protein kinase (MAPK) pathways leading to the transcriptional control of target genes involved in the scavenging or production of ROS. Here, oxidative signaling induced by exposure to excess Cd or Cu was investigated in relation to anti-oxidative defense responses to these metals. Three-week-old Arabidopsis thaliana plants were exposed to environmentally realistic concentrations of Cu and Cd and immediate responses were measured at the level of hydrogen peroxide (H 2 O 2 ) content, lipid peroxidation and transcript levels of genes involved in ROS homeostasis and signaling. Our findings show immediate (after 2 h exposure) effects in the roots following Cu exposure, whereas effects in the leaves were generally more delayed. Effects of Cd exposure in leaves and roots were observed only after 24 h exposure. On one hand, exposure of roots to Cu leads via activation of NADPH oxidases and Fenton reactions to H 2 O 2 production that can induce MAPK and oxylipin signaling to control the cellular redox status. On the other hand, conversion of H 2 O 2 to the more damaging hydroxyl radical by Fenton and Haber–Weiss reactions can initiate lipid peroxidation leading to membrane damage. In roots exposed to elevated Cd concentrations only oxidative signaling was initiated, possibly via NADPH oxidase-mediated ROS production. In leaves, time-dependent activation of MAPK and oxylipin signaling was seen after exposure to both metals, Cu or Cd, independent of changes in H 2 O 2 content." @default.
• W2059633974 created "2016-06-24" @default.
• W2059633974 creator A5008065198 @default.
• W2059633974 creator A5018758795 @default.
• W2059633974 creator A5038386582 @default.
• W2059633974 creator A5076252003 @default.
• W2059633974 creator A5085412403 @default.
• W2059633974 date "2012-11-01" @default.
• W2059633974 modified "2023-10-16" @default.
• W2059633974 title "Exposure of Arabidopsis thaliana to Cd or Cu excess leads to oxidative stress mediated alterations in MAPKinase transcript levels" @default.
• W2059633974 cites W1774180946 @default.
• W2059633974 cites W1968803817 @default.
• W2059633974 cites W1971798720 @default.
• W2059633974 cites W1983729367 @default.
• W2059633974 cites W1987438700 @default.
• W2059633974 cites W1993480266 @default.
• W2059633974 cites W1994410233 @default.
• W2059633974 cites W2004632808 @default.
• W2059633974 cites W2006935002 @default.
• W2059633974 cites W2008709229 @default.
• W2059633974 cites W2018939837 @default.
• W2059633974 cites W2022627071 @default.
• W2059633974 cites W2026552295 @default.
• W2059633974 cites W2032411337 @default.
• W2059633974 cites W2034294739 @default.
• W2059633974 cites W2035908878 @default.
• W2059633974 cites W2039734395 @default.
• W2059633974 cites W2041393831 @default.
• W2059633974 cites W2042245748 @default.
• W2059633974 cites W2042483895 @default.
• W2059633974 cites W2048403482 @default.
• W2059633974 cites W2054262102 @default.
• W2059633974 cites W2065706688 @default.
• W2059633974 cites W2068968614 @default.
• W2059633974 cites W2073720015 @default.
• W2059633974 cites W2077235164 @default.
• W2059633974 cites W2078656269 @default.
• W2059633974 cites W2081309732 @default.
• W2059633974 cites W2086491289 @default.
• W2059633974 cites W2090020964 @default.
• W2059633974 cites W2100945610 @default.
• W2059633974 cites W2101507920 @default.
• W2059633974 cites W2102709156 @default.
• W2059633974 cites W2108283825 @default.
• W2059633974 cites W2108652954 @default.
• W2059633974 cites W2111293030 @default.
• W2059633974 cites W2115507323 @default.
• W2059633974 cites W2118159036 @default.
• W2059633974 cites W2119326646 @default.
• W2059633974 cites W2125863862 @default.
• W2059633974 cites W2126473492 @default.
• W2059633974 cites W2126630551 @default.
• W2059633974 cites W2126648418 @default.
• W2059633974 cites W2131972635 @default.
• W2059633974 cites W2133760292 @default.
• W2059633974 cites W2136431988 @default.
• W2059633974 cites W2137904897 @default.
• W2059633974 cites W2139202993 @default.
• W2059633974 cites W2141389812 @default.
• W2059633974 cites W2142663875 @default.
• W2059633974 cites W2147863419 @default.
• W2059633974 cites W2149127266 @default.
• W2059633974 cites W2151585453 @default.
• W2059633974 cites W2154140763 @default.
• W2059633974 cites W2168753206 @default.
• W2059633974 doi "https://doi.org/10.1016/j.envexpbot.2012.04.003" @default.
• W2059633974 hasPublicationYear "2012" @default.
• W2059633974 type Work @default.
• W2059633974 sameAs 2059633974 @default.
• W2059633974 citedByCount "106" @default.
• W2059633974 countsByYear W20596339742012 @default.
• W2059633974 countsByYear W20596339742013 @default.
• W2059633974 countsByYear W20596339742014 @default.
• W2059633974 countsByYear W20596339742015 @default.
• W2059633974 countsByYear W20596339742016 @default.
• W2059633974 countsByYear W20596339742017 @default.
• W2059633974 countsByYear W20596339742018 @default.
• W2059633974 countsByYear W20596339742019 @default.
• W2059633974 countsByYear W20596339742020 @default.
• W2059633974 countsByYear W20596339742021 @default.
• W2059633974 countsByYear W20596339742022 @default.
• W2059633974 countsByYear W20596339742023 @default.
• W2059633974 crossrefType "journal-article" @default.
• W2059633974 hasAuthorship W2059633974A5008065198 @default.
• W2059633974 hasAuthorship W2059633974A5018758795 @default.
• W2059633974 hasAuthorship W2059633974A5038386582 @default.
• W2059633974 hasAuthorship W2059633974A5076252003 @default.
• W2059633974 hasAuthorship W2059633974A5085412403 @default.
• W2059633974 hasConcept C104317684 @default.
• W2059633974 hasConcept C143065580 @default.
• W2059633974 hasConcept C185592680 @default.
• W2059633974 hasConcept C2775988993 @default.
• W2059633974 hasConcept C2776151105 @default.
• W2059633974 hasConcept C2779491563 @default.
• W2059633974 hasConcept C2780829032 @default.
• W2059633974 hasConcept C48349386 @default.
• W2059633974 hasConcept C55493867 @default.
• W2059633974 hasConcept C57074206 @default.

• next