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• W2059644295 abstract "The changes induced by transient hypertension on cardiac structure and function are unclear. Pregnancy-induced hypertension offers a natural and spontaneous model of this condition. To assess the potential of echocardiographic Doppler to unmask left ventricular function impairment, we studied 28 women aged 26.4 ± 7.2 years with pregnancy-induced hypertension defined as blood pressure higher than 140/90 mm Hg in the third trimester of pregnancy without a history of hypertension. Twenty normal pregnant women, aged 27.5 ± 6.4 years, were the controls. Left ventricular diastolic diameter, fractional shortening, E velocity, A velocity, E/A ratio, isovolumetric relaxation time (IRT), isovolumetric contraction time (ICT), ejection time (ET), and the combined index of myocardial performance (Tei index = IRT + ICT/ET), were calculated by echocardiography Doppler 2 to 4 days postpartum. There were statistically significant differences between groups in the following parameters: E/A ratio: 1.3 ± 0.3 in pregnancy-induced hypertension v 1.5 ± 0.3 in normal pregnant women (P < .05), IRT: 104 ± 14 msec v 84 ± 7 msec (P < .000), and the Tei index: 0.51 ± 0.15 v 0.35 ± 0.04 (P < .00), respectively. According to this data pregnancy-induced hypertension evaluated 2 to 4 days after delivery showed left ventricular dysfunction, mainly diastolic. The IRT and the Tei index are the most useful echocardiographic parameters to unmask left ventricular dysfunction in pregnancy-induced hypertension. Am J Hypertens 2001;14:271–275 © 2001 American Journal of Hypertension, Ltd." @default.
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• W2059644295 date "2001-03-01" @default.
• W2059644295 modified "2023-10-08" @default.
• W2059644295 title "Left ventricular function impairment in pregnancy-induced hypertension" @default.
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• W2059644295 doi "https://doi.org/10.1016/s0895-7061(00)01264-4" @default.
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