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• W2059651708 abstract "No AccessJournal of UrologyPediatric Urology: Review Article1 Dec 1995Correction of Vesicoureteral Reflux in Children by Endoscopic Collagen Injection: A Prospective Study Mikko Reunane Mikko ReunaneMikko Reunane More articles by this author View All Author Informationhttps://doi.org/10.1016/S0022-5347(01)66720-XAboutFull TextPDF ToolsAdd to favoritesDownload CitationsTrack CitationsPermissionsReprints ShareFacebookLinked InTwitterEmail Abstract Purpose: The aim of our prospective study was to evaluate the long-term results of correction of vesicoureteral reflux in children by subureteral submucosal endoscopic collagen injection. Materials and Methods: Between May 1988 and June 1994, 197 refluxing ureters in 148 children (grade III or IV, international grading system) were treated by collagen injection. Injection was done using general anesthesia and repeated 1 or 2 times if reflux persisted on the 1-month followup radionuclide cystogram. Cystography was repeated at 6 months, 2 years and 4 years. Results: After 1 month, 6 months, 2 years and 4 years grades III and IV reflux were cured in 93.9 percent, 91.7 percent, 85.3 percent and 81.8 percent, respectively, of 132 simple ureters. For the 27 duplex ureters success rates were 44.4 percent, 25.9 percent, 23.1 percent and 21.4 percent, respectively, after 1 month, 6 months, 2 years and 4 years. After failed injections neo-implantation was performed with no difficulty. Conclusions: Our results show that in simple ureters reflux, especially grade III, can be corrected by collagen injection. Results seem to be stable after 2 years of followup. References 1 : Zur Pathologie der durch Bacterien bewirkten absteigenden Nephritis. 1883 Dissertation cited by Alksne. J.: Folia Urol.1907; 1: 338. Google Scholar 2 : Ureteroverletzung bei Laparatomie.. Zentralbl. Gynak.1893; 17: 97. Google Scholar 3 : Vesicoureteral reflux in children.. J. Urol.1955; 74: 607. 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J. Ped. Surg.1987; 22: 1087. Google Scholar 12 : Migration and granulomatous reaction after periurethral injection of Polytef (Teflon).. J.A.M.A.1984; 251: 3277. Google Scholar 13 : Migration and granulomatous reaction after intravesical/subureteric injection of polytef. J. Urol.1987; 137: 122A. abstract 74. Link, Google Scholar 14 : Long-term follow-up of tissue reactions caused by Teflon paste and cross-linked collagen in rats.. Ped. Surg. Int.1991; 6: 241. Google Scholar 15 : Long-term histological results following glutaraldehyde cross-linked collagen injection into the suburothelial space of the mini-pig bladder.. Ped. Surg. Int.1991; 6: 252. Google Scholar 16 : Results of endoscopic subureteral collagen injection for reflux correction in pigs and dogs.. Ped. Surg. Int.1991; 6: 261. Google Scholar 17 : Medical management of mild and moderate vesicoureteral reflux: followup studies of infants and young children.. A preliminary report of the Southwest Pediatric Nephrology Study Group. J. Urol.1992; 148: 1683. Google Scholar 18 : Migration of Polytef paste to the lung and brain following intravesical injection for the correction of reflux.. Ped. Surg. Int.1991; 6: 239. Google Scholar 19 : Limitations and alternatives to endoscopic correction of vesicoureteral reflux with Polytef paste.. Ped. Surg. Int.1989; 4: 149. Google Scholar 20 : Endoscopic injection of glutaraldehyde cross-linked bovine dermal collagen for correction of vesicoureteral reflux.. J. Urol.1991; 145: 115. Abstract, Google Scholar 21 : Subureteral collagen injection for the endoscopic treatment of vesicoureteral reflux in children. Followup study of 97 treated ureters and histological analysis of collagen implants.. J. Urol.1992; 148: 718. Abstract, Google Scholar Department of Pediatric Surgery, Turku University Central Hospital, Turku, Finland.© 1995 by American Urological Association, Inc.FiguresReferencesRelatedDetails Volume 154Issue 6December 1995Page: 2156-2158 Advertisement Copyright & Permissions© 1995 by American Urological Association, Inc.MetricsAuthor Information Mikko Reunane More articles by this author Expand All Advertisement PDF downloadLoading ..." @default.
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• W2059651708 title "Correction of Vesicoureteral Reflux in Children by Endoscopic Collagen Injection: A Prospective Study" @default.
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