Matches in SemOpenAlex for { <https://semopenalex.org/work/W2059653753> ?p ?o ?g. }
- W2059653753 endingPage "248" @default.
- W2059653753 startingPage "241" @default.
- W2059653753 abstract "Multiple Sclerosis (MS) is a heterogeneous disease and a variable percentage of patients are non-responders to common treatment. Early diagnosis of non-responders allows change to a more useful therapy for the patient and better allocates a large amount of financial resources. Quantification of Neutralizing antibodies (Nabs) and of biological activity of IFN-β are recognized approaches to identify immuno-pharmacological non-responders. A consistent number of studies have demonstrated that quantification of Myxovirus-induced protein A (MxA) is a valid biomarker to detect immune-pharmacological non responders after one year of treatment. Persistent high titre of Nabs and absence of biological activity predict abolition of IFN-β effects in disease activity measured through MRI, number of relapses and disability. Guidelines and flow-charts including both Nabs and MxA quantification are presented." @default.
- W2059653753 created "2016-06-24" @default.
- W2059653753 creator A5011959155 @default.
- W2059653753 creator A5018476900 @default.
- W2059653753 creator A5021825068 @default.
- W2059653753 creator A5042831260 @default.
- W2059653753 creator A5044776241 @default.
- W2059653753 creator A5047152967 @default.
- W2059653753 creator A5063684395 @default.
- W2059653753 creator A5064679267 @default.
- W2059653753 creator A5075124568 @default.
- W2059653753 creator A5081384901 @default.
- W2059653753 creator A5091238433 @default.
- W2059653753 date "2015-04-01" @default.
- W2059653753 modified "2023-10-16" @default.
- W2059653753 title "Biological monitoring of IFN-β therapy in Multiple Sclerosis" @default.
- W2059653753 cites W1552188382 @default.
- W2059653753 cites W1964445903 @default.
- W2059653753 cites W1969339244 @default.
- W2059653753 cites W1971219705 @default.
- W2059653753 cites W1973046191 @default.
- W2059653753 cites W1975857760 @default.
- W2059653753 cites W1975995030 @default.
- W2059653753 cites W1979137792 @default.
- W2059653753 cites W1979969759 @default.
- W2059653753 cites W1980076164 @default.
- W2059653753 cites W1982044564 @default.
- W2059653753 cites W1982833235 @default.
- W2059653753 cites W1983855969 @default.
- W2059653753 cites W1992829415 @default.
- W2059653753 cites W1993417921 @default.
- W2059653753 cites W1994936624 @default.
- W2059653753 cites W2001504083 @default.
- W2059653753 cites W2004723648 @default.
- W2059653753 cites W2006218745 @default.
- W2059653753 cites W2010143901 @default.
- W2059653753 cites W2010319943 @default.
- W2059653753 cites W2012971477 @default.
- W2059653753 cites W2016173904 @default.
- W2059653753 cites W2016531029 @default.
- W2059653753 cites W2020275618 @default.
- W2059653753 cites W2020952837 @default.
- W2059653753 cites W2023685327 @default.
- W2059653753 cites W2026903507 @default.
- W2059653753 cites W2029613564 @default.
- W2059653753 cites W2033519785 @default.
- W2059653753 cites W2034432056 @default.
- W2059653753 cites W2035167238 @default.
- W2059653753 cites W2039888078 @default.
- W2059653753 cites W2041844431 @default.
- W2059653753 cites W2046354075 @default.
- W2059653753 cites W2047200592 @default.
- W2059653753 cites W2047575804 @default.
- W2059653753 cites W2049515410 @default.
- W2059653753 cites W2053505020 @default.
- W2059653753 cites W2054843986 @default.
- W2059653753 cites W2059427914 @default.
- W2059653753 cites W2060526888 @default.
- W2059653753 cites W2066271685 @default.
- W2059653753 cites W2069946049 @default.
- W2059653753 cites W2073827812 @default.
- W2059653753 cites W2078442450 @default.
- W2059653753 cites W2082727602 @default.
- W2059653753 cites W2086149172 @default.
- W2059653753 cites W2086332151 @default.
- W2059653753 cites W2090602708 @default.
- W2059653753 cites W2091934161 @default.
- W2059653753 cites W2093942918 @default.
- W2059653753 cites W2095999740 @default.
- W2059653753 cites W2096569053 @default.
- W2059653753 cites W2101505589 @default.
- W2059653753 cites W2102121306 @default.
- W2059653753 cites W2104692290 @default.
- W2059653753 cites W2106710384 @default.
- W2059653753 cites W2119847512 @default.
- W2059653753 cites W2121385805 @default.
- W2059653753 cites W2126586565 @default.
- W2059653753 cites W2129012981 @default.
- W2059653753 cites W2132640969 @default.
- W2059653753 cites W2133141213 @default.
- W2059653753 cites W2137782187 @default.
- W2059653753 cites W2141845754 @default.
- W2059653753 cites W2145748636 @default.
- W2059653753 cites W2146867140 @default.
- W2059653753 cites W2149017348 @default.
- W2059653753 cites W2150534199 @default.
- W2059653753 cites W2151491950 @default.
- W2059653753 cites W2151601574 @default.
- W2059653753 cites W2151962039 @default.
- W2059653753 cites W2161552221 @default.
- W2059653753 cites W2164490190 @default.
- W2059653753 cites W2169604625 @default.
- W2059653753 cites W2171104471 @default.
- W2059653753 cites W2174908949 @default.
- W2059653753 cites W2175739361 @default.
- W2059653753 cites W2316803406 @default.
- W2059653753 cites W2331354957 @default.
- W2059653753 cites W2485483395 @default.