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- W2059657030 abstract "Abstract Efficient lysogenization of Escherichia coli K12 by bacteriophage λ requires the high level of synthesis of the phage repressor shortly after infection. This high level of synthesis of repressor requires the action of the λ eII and cIII proteins. Certain mutants of λ (λcIIIs) appear to have excess c II c III activity and can lysogenize more efficiently than λ+. The basis for the enhanced lysogenization is that, while two or more infecting phage are necessary for λ+ to lysogenize, a single infecting λcIIIs particle is sufficient for lysogenization. Also, repressor levels in cells infected with λcIIIs are higher than in those infected with λ+. I report here that repressor overproduction by λcIIIs (1) is due to a much higher rate of repressor synthesis than that of λ+; (2) is most marked at low multiplicities of infection, possibly because λcIIIs produces repressor much more efficiently than λ+ as a singly infecting phage." @default.
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- W2059657030 date "1979-08-01" @default.
- W2059657030 modified "2023-09-26" @default.
- W2059657030 title "An analysis of repressor overproduction by the λ cIIIs mutant" @default.
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- W2059657030 doi "https://doi.org/10.1016/0022-2836(79)90276-6" @default.
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