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- W2059659417 abstract "THE DEVELOPMENT OF REPRODUCTIVE FUNCTION in female rats is materially altered by the injection of testosterone compounds during the first weeks of postnatal life (1–4). When these animals reach adulthood they show abnormalities in several features of reproductive structure and function. They do not display cyclic mating behavior; ovulation and corpus luteum formation do not occur; the uterus differentiates atypically and is not normally responsive to estrogen. When such animals are spayed and injected with estrogen and progesterone estrous behavior is not induced even with 10 times the quantity of hormone (3) which causes heat in control animals. It was concluded from these studies that testosterone propionate in doses from 3 to 36 mg. is effective in suppressing reproductive function when the injections are begun soon after birthOn the other hand, these androgens when given to sexually mature." @default.
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- W2059659417 date "1941-11-01" @default.
- W2059659417 modified "2023-10-06" @default.
- W2059659417 title "INFLUENCE OF AGE AND PRESENCE OF THE OVARIES ON REPRODUCTIVE FUNCTION IN RATS INJECTED WITH ANDROGENS<sup>1</sup>" @default.
- W2059659417 doi "https://doi.org/10.1210/endo-29-5-784" @default.
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