Matches in SemOpenAlex for { <https://semopenalex.org/work/W2059698538> ?p ?o ?g. }
- W2059698538 endingPage "1395" @default.
- W2059698538 startingPage "1388" @default.
- W2059698538 abstract "Major changes have taken place within the last few years in the management of follicular lymphoma (FL) leading to substantial improvement in prognosis and overall survival. For some patients with limited disease stages I and II, radiotherapy may be associated with durable responses; however, it is unclear whether patients are cured and new approaches such as the combination of irradiation with rituximab or even single-agent rituximab need to be explored. Whereas watch and wait is the current standard for stage III and IV disease with low tumour burden, better indices are warranted to potentially select patients for whom early intervention is preferred. For advanced stages with a high tumour burden, immunochemotherapy followed by 2 years of rituximab maintenance is widely accepted as standard therapy, although re-treatment at recurrence may be an alternative option. Highly attractive new therapeutic options have recently arisen from new antibodies, and from new agents targeting oncogenic pathways such as B-cell receptor signalling pathways or inhibition of bcl 2. Furthermore, immunomodulatory drugs may add to the therapeutic armamentarium and may lead to ‘chemotherapy-free’ therapies in the near future. Hence, the management of FLs has become a moving target and the hope is justified that the long-term perspectives of patients suffering from the disease will be further improved in the near future." @default.
- W2059698538 created "2016-06-24" @default.
- W2059698538 creator A5033935778 @default.
- W2059698538 creator A5082606841 @default.
- W2059698538 date "2014-02-28" @default.
- W2059698538 modified "2023-10-13" @default.
- W2059698538 title "How we manage follicular lymphoma" @default.
- W2059698538 cites W13575375 @default.
- W2059698538 cites W1503750180 @default.
- W2059698538 cites W1504115866 @default.
- W2059698538 cites W1515092594 @default.
- W2059698538 cites W1589631234 @default.
- W2059698538 cites W1700709632 @default.
- W2059698538 cites W1964838088 @default.
- W2059698538 cites W1965867669 @default.
- W2059698538 cites W1970568669 @default.
- W2059698538 cites W1970648523 @default.
- W2059698538 cites W1976402300 @default.
- W2059698538 cites W1979753334 @default.
- W2059698538 cites W1982790762 @default.
- W2059698538 cites W1984561196 @default.
- W2059698538 cites W1988367968 @default.
- W2059698538 cites W1991361673 @default.
- W2059698538 cites W1991644988 @default.
- W2059698538 cites W2001302091 @default.
- W2059698538 cites W2007416864 @default.
- W2059698538 cites W2007627691 @default.
- W2059698538 cites W2009937603 @default.
- W2059698538 cites W2012232903 @default.
- W2059698538 cites W2014654561 @default.
- W2059698538 cites W2019874087 @default.
- W2059698538 cites W2036879468 @default.
- W2059698538 cites W2037252592 @default.
- W2059698538 cites W2045330558 @default.
- W2059698538 cites W2048773859 @default.
- W2059698538 cites W2050355959 @default.
- W2059698538 cites W2052164658 @default.
- W2059698538 cites W2064731149 @default.
- W2059698538 cites W2067149832 @default.
- W2059698538 cites W2073019775 @default.
- W2059698538 cites W2074519099 @default.
- W2059698538 cites W2075141373 @default.
- W2059698538 cites W2080877772 @default.
- W2059698538 cites W2086429132 @default.
- W2059698538 cites W2092503047 @default.
- W2059698538 cites W2097346190 @default.
- W2059698538 cites W2101340254 @default.
- W2059698538 cites W2101648653 @default.
- W2059698538 cites W2104334201 @default.
- W2059698538 cites W2105397991 @default.
- W2059698538 cites W2105549867 @default.
- W2059698538 cites W2109205360 @default.
- W2059698538 cites W2109331739 @default.
- W2059698538 cites W2109658051 @default.
- W2059698538 cites W2111779647 @default.
- W2059698538 cites W2112317958 @default.
- W2059698538 cites W2114233385 @default.
- W2059698538 cites W2116194748 @default.
- W2059698538 cites W2116573634 @default.
- W2059698538 cites W2118495504 @default.
- W2059698538 cites W2121227413 @default.
- W2059698538 cites W2125354192 @default.
- W2059698538 cites W2125904077 @default.
- W2059698538 cites W2126529136 @default.
- W2059698538 cites W2126855868 @default.
- W2059698538 cites W2132443196 @default.
- W2059698538 cites W2132598458 @default.
- W2059698538 cites W2133201432 @default.
- W2059698538 cites W2134090290 @default.
- W2059698538 cites W2134566706 @default.
- W2059698538 cites W2134752918 @default.
- W2059698538 cites W2135321054 @default.
- W2059698538 cites W2136326451 @default.
- W2059698538 cites W2138404218 @default.
- W2059698538 cites W2138498369 @default.
- W2059698538 cites W2138881579 @default.
- W2059698538 cites W2141097257 @default.
- W2059698538 cites W2141200671 @default.
- W2059698538 cites W2141593354 @default.
- W2059698538 cites W2144010959 @default.
- W2059698538 cites W2145604368 @default.
- W2059698538 cites W2152996672 @default.
- W2059698538 cites W2153921055 @default.
- W2059698538 cites W2154643481 @default.
- W2059698538 cites W2155654259 @default.
- W2059698538 cites W2155724413 @default.
- W2059698538 cites W2156522119 @default.
- W2059698538 cites W2158424965 @default.
- W2059698538 cites W2159567369 @default.
- W2059698538 cites W2159982513 @default.
- W2059698538 cites W2161054245 @default.
- W2059698538 cites W2165117825 @default.
- W2059698538 cites W2165279742 @default.
- W2059698538 cites W2168781524 @default.
- W2059698538 cites W2169209759 @default.
- W2059698538 cites W2169578616 @default.
- W2059698538 cites W2171522825 @default.
- W2059698538 cites W2171771895 @default.