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• W2059707923 endingPage "e88763" @default.
• W2059707923 startingPage "e88763" @default.
• W2059707923 abstract "This study aims to investigate the neurostructural foundations of the human personality in young adults. High-resolution structural T1-weighted MR images of 71 healthy young individuals were processed using voxel-based morphometric (VBM) approach. Multiple regression analyses were performed to identify the associations between personality traits and gray matter volume (GMV). The Eysenck Personality Questionnaire-Revised, Short Scale for Chinese was chosen to assess the personality traits. This scale includes four dimensions, namely, extraversion, neuroticism, psychoticism, and lie. Particularly, we studied on two dimensions (extraversion and neuroticism) of Eysenck's personality. Our results showed that extraversion was negatively correlated with GMV of the bilateral amygdala, the bilateral parahippocampal gyrus, the right middle temporal gyrus, and the left superior frontal gyrus, all of which are involved in emotional and social cognitive processes. These results might suggest an association between extraversion and affective processing. In addition, a positive correlation was detected between neuroticism and GMV of the right cerebellum, a key brain region for negative affect coordination. Meanwhile, a negative association was revealed between GMV of the left superior frontal gyrus and neuroticism. These results may prove that neuroticism is related to several brain regions involved in regulating negative emotions. Based on those findings, we concluded that brain regions involved in social cognition and affective process accounted for modulation and shaping of personality traits among young individuals. Results of this study may serve as a basis for elucidating the anatomical factors of personality." @default.
• W2059707923 created "2016-06-24" @default.
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• W2059707923 date "2014-02-14" @default.
• W2059707923 modified "2023-09-28" @default.
• W2059707923 title "Relationship between Personality and Gray Matter Volume in Healthy Young Adults: A Voxel-Based Morphometric Study" @default.
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• W2059707923 doi "https://doi.org/10.1371/journal.pone.0088763" @default.
• W2059707923 hasPubMedCentralId "https://www.ncbi.nlm.nih.gov/pmc/articles/3925163" @default.
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• W2059707923 hasPublicationYear "2014" @default.
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