Matches in SemOpenAlex for { <https://semopenalex.org/work/W2059711700> ?p ?o ?g. }
Showing items 1 to 85 of
85
with 100 items per page.
- W2059711700 endingPage "478" @default.
- W2059711700 startingPage "473" @default.
- W2059711700 abstract "Routine urine cytology is not particularly useful as a screening test for urinary tract malignancy in the general population, due to its low detection rate. Bladder, ureteral, and pelvic lavage and flow cytometry increased the test sensitivity but could be applied only to a limited number of patients. A simple, sensitive screening test is needed.Two hundred eighty-two urine samples from 146 patients from the Urology Tumor Clinic patients during their initial visits were subject to cytologic evaluation and measurement of the activity of endogenous beta-glucuronidase, followed by confirmation procedures, including cystoscopy with biopsy, ultrasonography, radiography and/or computed tomography.Among 146 patients, 32 had confirmed transitional cell carcinoma and 14 renal cell carcinoma. The urinary beta-glucuronidase activity was higher in patients with cancer than in those without cancer in the Urology Service and in 80 normal healthy control subjects. The accuracy of the urine enzyme diagnostic system measured by the receiver-operating characteristic (ROC) plot was 98% or higher based on the number of patients. The upper threshold value determined by ROC analysis was 1.7 nmol/min/mumol creatinine. At this threshold value, the sensitivities of the enzyme assay for transitional cell carcinoma, renal cell carcinoma, and all cancers were, respectively, 94%, 98%, and 95%. These values were much higher than the corresponding sensitivities of urine cytology: 41%, 0%, and 22%.Urinary beta-glucuronidase is a much more sensitive test to screen for urinary tract malignancy than routine urine cytology in high risk patients, provided that a positive test is followed by diagnostic procedures for confirmation." @default.
- W2059711700 created "2016-06-24" @default.
- W2059711700 creator A5009665204 @default.
- W2059711700 creator A5058996987 @default.
- W2059711700 date "1995-08-01" @default.
- W2059711700 modified "2023-09-27" @default.
- W2059711700 title "Urinary beta-glucuronidase activity as an initial screening test for urinary tract malignancy in high risk patients. Comparison with conventional urine cytologic evaluation" @default.
- W2059711700 cites W187523876 @default.
- W2059711700 cites W1965426444 @default.
- W2059711700 cites W1968114652 @default.
- W2059711700 cites W1990748933 @default.
- W2059711700 cites W2048064160 @default.
- W2059711700 cites W2063989659 @default.
- W2059711700 cites W2066541202 @default.
- W2059711700 cites W2092713296 @default.
- W2059711700 cites W2102150307 @default.
- W2059711700 cites W2104960492 @default.
- W2059711700 cites W2410297690 @default.
- W2059711700 cites W2432479288 @default.
- W2059711700 cites W2460046246 @default.
- W2059711700 cites W2466983811 @default.
- W2059711700 cites W3319003 @default.
- W2059711700 cites W82642371 @default.
- W2059711700 doi "https://doi.org/10.1002/1097-0142(19950801)76:3<473::aid-cncr2820760318>3.0.co;2-6" @default.
- W2059711700 hasPubMedId "https://pubmed.ncbi.nlm.nih.gov/8625129" @default.
- W2059711700 hasPublicationYear "1995" @default.
- W2059711700 type Work @default.
- W2059711700 sameAs 2059711700 @default.
- W2059711700 citedByCount "11" @default.
- W2059711700 countsByYear W20597117002013 @default.
- W2059711700 countsByYear W20597117002016 @default.
- W2059711700 crossrefType "journal-article" @default.
- W2059711700 hasAuthorship W2059711700A5009665204 @default.
- W2059711700 hasAuthorship W2059711700A5058996987 @default.
- W2059711700 hasBestOaLocation W20597117001 @default.
- W2059711700 hasConcept C121608353 @default.
- W2059711700 hasConcept C126322002 @default.
- W2059711700 hasConcept C126894567 @default.
- W2059711700 hasConcept C142724271 @default.
- W2059711700 hasConcept C18823058 @default.
- W2059711700 hasConcept C2777548846 @default.
- W2059711700 hasConcept C2778065480 @default.
- W2059711700 hasConcept C2778769751 @default.
- W2059711700 hasConcept C2779399171 @default.
- W2059711700 hasConcept C2780026642 @default.
- W2059711700 hasConcept C2780352672 @default.
- W2059711700 hasConcept C71924100 @default.
- W2059711700 hasConcept C77411442 @default.
- W2059711700 hasConcept C90924648 @default.
- W2059711700 hasConceptScore W2059711700C121608353 @default.
- W2059711700 hasConceptScore W2059711700C126322002 @default.
- W2059711700 hasConceptScore W2059711700C126894567 @default.
- W2059711700 hasConceptScore W2059711700C142724271 @default.
- W2059711700 hasConceptScore W2059711700C18823058 @default.
- W2059711700 hasConceptScore W2059711700C2777548846 @default.
- W2059711700 hasConceptScore W2059711700C2778065480 @default.
- W2059711700 hasConceptScore W2059711700C2778769751 @default.
- W2059711700 hasConceptScore W2059711700C2779399171 @default.
- W2059711700 hasConceptScore W2059711700C2780026642 @default.
- W2059711700 hasConceptScore W2059711700C2780352672 @default.
- W2059711700 hasConceptScore W2059711700C71924100 @default.
- W2059711700 hasConceptScore W2059711700C77411442 @default.
- W2059711700 hasConceptScore W2059711700C90924648 @default.
- W2059711700 hasIssue "3" @default.
- W2059711700 hasLocation W20597117001 @default.
- W2059711700 hasLocation W20597117002 @default.
- W2059711700 hasOpenAccess W2059711700 @default.
- W2059711700 hasPrimaryLocation W20597117001 @default.
- W2059711700 hasRelatedWork W1937753434 @default.
- W2059711700 hasRelatedWork W1974653401 @default.
- W2059711700 hasRelatedWork W1976830962 @default.
- W2059711700 hasRelatedWork W2011149565 @default.
- W2059711700 hasRelatedWork W2026736918 @default.
- W2059711700 hasRelatedWork W2040074305 @default.
- W2059711700 hasRelatedWork W2043852318 @default.
- W2059711700 hasRelatedWork W2085161087 @default.
- W2059711700 hasRelatedWork W2393759260 @default.
- W2059711700 hasRelatedWork W2784942460 @default.
- W2059711700 hasVolume "76" @default.
- W2059711700 isParatext "false" @default.
- W2059711700 isRetracted "false" @default.
- W2059711700 magId "2059711700" @default.
- W2059711700 workType "article" @default.