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- W2059749939 abstract "Alzheimer's disease is a progressive neurodegenerative disorder and the most common form of dementia. The disease is confirmed by the presence of neuritic plaques and neurofibrillary tangles in the cerebral cortex at autopsy, but the accuracy of antemortem diagnosis, especially at the early stages of the disease, is not ideal. Thus, there is a substantial need for the discovery and validation of diagnostic biomarkers. Many Alzheimer's disease biomarker discovery studies emphasize the analysis of cerebrospinal fluid (CSF) because of its close association with the brain. Here, we review recent mass spectrometry-based studies of Alzheimer's disease CSF, and additionally discuss issues associated with CSF in proteomics studies." @default.
- W2059749939 created "2016-06-24" @default.
- W2059749939 creator A5004154660 @default.
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- W2059749939 date "2010-12-01" @default.
- W2059749939 modified "2023-10-09" @default.
- W2059749939 title "Recent cerebrospinal fluid biomarker studies of Alzheimer’s disease" @default.
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- W2059749939 doi "https://doi.org/10.1586/epr.10.75" @default.
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