FRINK Linked Data Fragments server

Matches in SemOpenAlex for { <https://semopenalex.org/work/W2059769534> ?p ?o ?g. }

• W2059769534 endingPage "184" @default.
• W2059769534 startingPage "177" @default.
• W2059769534 abstract "Abstract Objectives: B‐cell activating factor of the tumor necrosis factor family (BAFF) and a proliferation‐inducing ligand (APRIL) regulate survival and proliferation of B cells. Thus the association of elevated serum levels of BAFF and APRIL with worse prognosis has been suggested in B‐cell lymphoid malignancies. However, the prognostic relevance of BAFF and APRIL is unknown in patients treated with rituximab, a monoclonal antibody targeting B‐cell depletion. Methods: We measured serum levels of BAFF and APRIL by enzyme‐linked immunosorbent assay in 66 patients newly diagnosed as diffuse large B‐cell lymphoma (DLBCL). All patients were treated with rituximab‐CHOP chemotherapy. Results: The mean (±standard deviation) serum level of BAFF (1 970.21 ± 1 979.45 pg/mL) was higher in DLBCL than in controls (861.03 ± 194.92 pg/mL, Mann–Whitney U ‐test, P < 0.001). When the patients were dichotomized into high and low BAFF group based on the median value (1 258.00 pg/mL), high BAFF group had less numbers of complete responders to rituximab‐CHOP, and more relapses or progression after or during treatment. In multivariate analysis, serum BAFF was an independent prognostic factor for overall survival and progression‐free survival ( P < 0.05). Although serum levels of APRIL was also higher than controls (10.60 ± 19.08 ng/mL vs. 1.10 ± 0.30 ng/mL, P = 0.023), it failed to show prognostic significance. Conclusions: Serum BAFF may be a useful indicator predicting prognosis in DLBCL patients treated with rituximab‐containing chemotherapy." @default.
• W2059769534 created "2016-06-24" @default.
• W2059769534 creator A5000449107 @default.
• W2059769534 creator A5004166441 @default.
• W2059769534 creator A5021404268 @default.
• W2059769534 creator A5023527480 @default.
• W2059769534 creator A5027473085 @default.
• W2059769534 creator A5050297282 @default.
• W2059769534 creator A5065717188 @default.
• W2059769534 creator A5076747241 @default.
• W2059769534 creator A5081706948 @default.
• W2059769534 date "2008-08-07" @default.
• W2059769534 modified "2023-10-12" @default.
• W2059769534 title "Serum BAFF predicts prognosis better than APRIL in diffuse large B-cell lymphoma patients treated with rituximab plus CHOP chemotherapy" @default.
• W2059769534 cites W1514511317 @default.
• W2059769534 cites W1543542866 @default.
• W2059769534 cites W1975249184 @default.
• W2059769534 cites W2007998723 @default.
• W2059769534 cites W2013296669 @default.
• W2059769534 cites W2021932553 @default.
• W2059769534 cites W2024372250 @default.
• W2059769534 cites W2024884089 @default.
• W2059769534 cites W2058663390 @default.
• W2059769534 cites W2070135451 @default.
• W2059769534 cites W2086765333 @default.
• W2059769534 cites W2088568397 @default.
• W2059769534 cites W2102162920 @default.
• W2059769534 cites W2113737833 @default.
• W2059769534 cites W2119170361 @default.
• W2059769534 cites W2136426653 @default.
• W2059769534 cites W2150429309 @default.
• W2059769534 cites W2152330468 @default.
• W2059769534 cites W2156358796 @default.
• W2059769534 cites W2165056939 @default.
• W2059769534 cites W2166022914 @default.
• W2059769534 cites W2166397226 @default.
• W2059769534 cites W2167274549 @default.
• W2059769534 doi "https://doi.org/10.1111/j.1600-0609.2008.01099.x" @default.
• W2059769534 hasPubMedId "https://pubmed.ncbi.nlm.nih.gov/18510703" @default.
• W2059769534 hasPublicationYear "2008" @default.
• W2059769534 type Work @default.
• W2059769534 sameAs 2059769534 @default.
• W2059769534 citedByCount "30" @default.
• W2059769534 countsByYear W20597695342012 @default.
• W2059769534 countsByYear W20597695342014 @default.
• W2059769534 countsByYear W20597695342015 @default.
• W2059769534 countsByYear W20597695342016 @default.
• W2059769534 countsByYear W20597695342019 @default.
• W2059769534 countsByYear W20597695342020 @default.
• W2059769534 countsByYear W20597695342021 @default.
• W2059769534 countsByYear W20597695342023 @default.
• W2059769534 crossrefType "journal-article" @default.
• W2059769534 hasAuthorship W2059769534A5000449107 @default.
• W2059769534 hasAuthorship W2059769534A5004166441 @default.
• W2059769534 hasAuthorship W2059769534A5021404268 @default.
• W2059769534 hasAuthorship W2059769534A5023527480 @default.
• W2059769534 hasAuthorship W2059769534A5027473085 @default.
• W2059769534 hasAuthorship W2059769534A5050297282 @default.
• W2059769534 hasAuthorship W2059769534A5065717188 @default.
• W2059769534 hasAuthorship W2059769534A5076747241 @default.
• W2059769534 hasAuthorship W2059769534A5081706948 @default.
• W2059769534 hasConcept C126322002 @default.
• W2059769534 hasConcept C143998085 @default.
• W2059769534 hasConcept C159654299 @default.
• W2059769534 hasConcept C170286685 @default.
• W2059769534 hasConcept C203014093 @default.
• W2059769534 hasConcept C2776694085 @default.
• W2059769534 hasConcept C2778453870 @default.
• W2059769534 hasConcept C2778559949 @default.
• W2059769534 hasConcept C2779338263 @default.
• W2059769534 hasConcept C2779714933 @default.
• W2059769534 hasConcept C2779725641 @default.
• W2059769534 hasConcept C2780653079 @default.
• W2059769534 hasConcept C71924100 @default.
• W2059769534 hasConcept C90924648 @default.
• W2059769534 hasConceptScore W2059769534C126322002 @default.
• W2059769534 hasConceptScore W2059769534C143998085 @default.
• W2059769534 hasConceptScore W2059769534C159654299 @default.
• W2059769534 hasConceptScore W2059769534C170286685 @default.
• W2059769534 hasConceptScore W2059769534C203014093 @default.
• W2059769534 hasConceptScore W2059769534C2776694085 @default.
• W2059769534 hasConceptScore W2059769534C2778453870 @default.
• W2059769534 hasConceptScore W2059769534C2778559949 @default.
• W2059769534 hasConceptScore W2059769534C2779338263 @default.
• W2059769534 hasConceptScore W2059769534C2779714933 @default.
• W2059769534 hasConceptScore W2059769534C2779725641 @default.
• W2059769534 hasConceptScore W2059769534C2780653079 @default.
• W2059769534 hasConceptScore W2059769534C71924100 @default.
• W2059769534 hasConceptScore W2059769534C90924648 @default.
• W2059769534 hasIssue "3" @default.
• W2059769534 hasLocation W20597695341 @default.
• W2059769534 hasLocation W20597695342 @default.
• W2059769534 hasOpenAccess W2059769534 @default.
• W2059769534 hasPrimaryLocation W20597695341 @default.
• W2059769534 hasRelatedWork W2075609648 @default.
• W2059769534 hasRelatedWork W2124724259 @default.
• W2059769534 hasRelatedWork W2288194547 @default.
• W2059769534 hasRelatedWork W2334374063 @default.

• next