Matches in SemOpenAlex for { <https://semopenalex.org/work/W2059773032> ?p ?o ?g. }
Showing items 1 to 88 of
88
with 100 items per page.
- W2059773032 endingPage "2570" @default.
- W2059773032 startingPage "2561" @default.
- W2059773032 abstract "There is a difference between in vitro and in vivo measurements of the extent of enzyme induction. To explain this disparity we have measured changes in liver blood flow produced by three inducing agents—phenobarbitone (30 mg/kg for 4 days), antipyrine (30 mg/kg for 4 days) and 3,4-benzpyrene (40 mg/kg as a single injection). Flow was measured by a heat exchange method in conscious rats. Liver blood flow increased by 33–175 per cent above control values in rats treated with phenobarbitone and antipyrine but not in those given benzpyrene. The increase in liver blood flow was first seen at 24 hr and remained above control values for 2–8 days after treatment. In similarly operated rats phenobarbitone shortened the sleeping time to 5–10 per cent of control values with a similar time course to the changes in liver blood flow. The maximal velocity of N-demethylation of ethylmorphine increased from 4.9 to 17.2 nm/mg protein/min, the maximal increase occurring 2–3 days after starting phenobarbitone. It is suggested that the increase in liver blood flow may be due to increases in liver weight and enzyme activity." @default.
- W2059773032 created "2016-06-24" @default.
- W2059773032 creator A5014216602 @default.
- W2059773032 creator A5018218778 @default.
- W2059773032 creator A5059808176 @default.
- W2059773032 creator A5082661034 @default.
- W2059773032 date "1971-10-01" @default.
- W2059773032 modified "2023-10-15" @default.
- W2059773032 title "Changes in liver blood flow during enzyme induction" @default.
- W2059773032 cites W1488511002 @default.
- W2059773032 cites W1775749144 @default.
- W2059773032 cites W1951469402 @default.
- W2059773032 cites W1968760879 @default.
- W2059773032 cites W1983930203 @default.
- W2059773032 cites W1986959288 @default.
- W2059773032 cites W1991915665 @default.
- W2059773032 cites W1999725745 @default.
- W2059773032 cites W2005317666 @default.
- W2059773032 cites W2007995151 @default.
- W2059773032 cites W2014703611 @default.
- W2059773032 cites W2072092616 @default.
- W2059773032 cites W2080372958 @default.
- W2059773032 cites W2086841970 @default.
- W2059773032 doi "https://doi.org/10.1016/0006-2952(71)90164-x" @default.
- W2059773032 hasPubMedId "https://pubmed.ncbi.nlm.nih.gov/5114497" @default.
- W2059773032 hasPublicationYear "1971" @default.
- W2059773032 type Work @default.
- W2059773032 sameAs 2059773032 @default.
- W2059773032 citedByCount "90" @default.
- W2059773032 crossrefType "journal-article" @default.
- W2059773032 hasAuthorship W2059773032A5014216602 @default.
- W2059773032 hasAuthorship W2059773032A5018218778 @default.
- W2059773032 hasAuthorship W2059773032A5059808176 @default.
- W2059773032 hasAuthorship W2059773032A5082661034 @default.
- W2059773032 hasConcept C104317684 @default.
- W2059773032 hasConcept C126322002 @default.
- W2059773032 hasConcept C132154277 @default.
- W2059773032 hasConcept C134018914 @default.
- W2059773032 hasConcept C150194340 @default.
- W2059773032 hasConcept C150903083 @default.
- W2059773032 hasConcept C158846371 @default.
- W2059773032 hasConcept C181199279 @default.
- W2059773032 hasConcept C185592680 @default.
- W2059773032 hasConcept C190727270 @default.
- W2059773032 hasConcept C202199734 @default.
- W2059773032 hasConcept C207001950 @default.
- W2059773032 hasConcept C3020359197 @default.
- W2059773032 hasConcept C55493867 @default.
- W2059773032 hasConcept C71924100 @default.
- W2059773032 hasConcept C86803240 @default.
- W2059773032 hasConceptScore W2059773032C104317684 @default.
- W2059773032 hasConceptScore W2059773032C126322002 @default.
- W2059773032 hasConceptScore W2059773032C132154277 @default.
- W2059773032 hasConceptScore W2059773032C134018914 @default.
- W2059773032 hasConceptScore W2059773032C150194340 @default.
- W2059773032 hasConceptScore W2059773032C150903083 @default.
- W2059773032 hasConceptScore W2059773032C158846371 @default.
- W2059773032 hasConceptScore W2059773032C181199279 @default.
- W2059773032 hasConceptScore W2059773032C185592680 @default.
- W2059773032 hasConceptScore W2059773032C190727270 @default.
- W2059773032 hasConceptScore W2059773032C202199734 @default.
- W2059773032 hasConceptScore W2059773032C207001950 @default.
- W2059773032 hasConceptScore W2059773032C3020359197 @default.
- W2059773032 hasConceptScore W2059773032C55493867 @default.
- W2059773032 hasConceptScore W2059773032C71924100 @default.
- W2059773032 hasConceptScore W2059773032C86803240 @default.
- W2059773032 hasIssue "10" @default.
- W2059773032 hasLocation W20597730321 @default.
- W2059773032 hasLocation W20597730322 @default.
- W2059773032 hasOpenAccess W2059773032 @default.
- W2059773032 hasPrimaryLocation W20597730321 @default.
- W2059773032 hasRelatedWork W2015316225 @default.
- W2059773032 hasRelatedWork W2061511535 @default.
- W2059773032 hasRelatedWork W2313572343 @default.
- W2059773032 hasRelatedWork W2322869654 @default.
- W2059773032 hasRelatedWork W2400078816 @default.
- W2059773032 hasRelatedWork W2404991622 @default.
- W2059773032 hasRelatedWork W2407208628 @default.
- W2059773032 hasRelatedWork W2408436582 @default.
- W2059773032 hasRelatedWork W4289968013 @default.
- W2059773032 hasRelatedWork W4300641166 @default.
- W2059773032 hasVolume "20" @default.
- W2059773032 isParatext "false" @default.
- W2059773032 isRetracted "false" @default.
- W2059773032 magId "2059773032" @default.
- W2059773032 workType "article" @default.