Matches in SemOpenAlex for { <https://semopenalex.org/work/W2059781616> ?p ?o ?g. }
Showing items 1 to 95 of
95
with 100 items per page.
- W2059781616 endingPage "637" @default.
- W2059781616 startingPage "633" @default.
- W2059781616 abstract "Smoking by pregnant women poses a potential risk on the unborn child because nicotine can easily be transported from the maternal to the fetal physiological system. Our previous studies have shown that developing brains are sensitive to nicotine-induced cell loss if nicotine was administered during the brain growth spurt (early postnatal) in a rat model system. The purpose of this study was to examine whether nicotine exposure prenatally (first two trimesters equivalent in rats) would lead to Purkinje cell loss in the developing cerebellar vermis. Pregnant female rats were subcutaneously implanted with 0 (placebo), 15 (NIC 15), or 25 (NIC 25) mg nicotine pellets (21-day time released) on gestational day (GD) 0. An additional control group receiving no implantation was also introduced (normal). One pup from each litter was sacrificed on postnatal day (PD) 10 and the cerebellar vermis was processed for stereological cell counting of Purkinje cells. No significant effects of prenatal nicotine treatment were found in the forebrain, cerebellum, and brainstem weights. Similarly, the assessments of volume, Purkinje cell number, and Purkinje cell density found no significant differences among all treatment groups. Taken together, the current and a previous finding, it suggests that there is a temporal window of vulnerability to nicotine-induced Purkinje cell loss in the developing cerebellar vermis." @default.
- W2059781616 created "2016-06-24" @default.
- W2059781616 creator A5051886378 @default.
- W2059781616 creator A5080179653 @default.
- W2059781616 date "2003-09-01" @default.
- W2059781616 modified "2023-09-25" @default.
- W2059781616 title "Prenatal nicotine exposure does not cause Purkinje cell loss in the developing rat cerebellar vermis" @default.
- W2059781616 cites W1810757416 @default.
- W2059781616 cites W1966750374 @default.
- W2059781616 cites W1980556104 @default.
- W2059781616 cites W1981943300 @default.
- W2059781616 cites W1984913395 @default.
- W2059781616 cites W1992104052 @default.
- W2059781616 cites W2014892312 @default.
- W2059781616 cites W2019412495 @default.
- W2059781616 cites W2026002815 @default.
- W2059781616 cites W2027006026 @default.
- W2059781616 cites W2027184542 @default.
- W2059781616 cites W2030092107 @default.
- W2059781616 cites W2031963293 @default.
- W2059781616 cites W2034270961 @default.
- W2059781616 cites W2034353097 @default.
- W2059781616 cites W2037441262 @default.
- W2059781616 cites W2044175751 @default.
- W2059781616 cites W2053353301 @default.
- W2059781616 cites W2080527942 @default.
- W2059781616 cites W2084933994 @default.
- W2059781616 cites W2095586273 @default.
- W2059781616 cites W2138301950 @default.
- W2059781616 cites W2155157168 @default.
- W2059781616 cites W2169053074 @default.
- W2059781616 cites W91954215 @default.
- W2059781616 doi "https://doi.org/10.1016/s0892-0362(03)00048-5" @default.
- W2059781616 hasPubMedId "https://pubmed.ncbi.nlm.nih.gov/12972077" @default.
- W2059781616 hasPublicationYear "2003" @default.
- W2059781616 type Work @default.
- W2059781616 sameAs 2059781616 @default.
- W2059781616 citedByCount "9" @default.
- W2059781616 countsByYear W20597816162013 @default.
- W2059781616 countsByYear W20597816162015 @default.
- W2059781616 crossrefType "journal-article" @default.
- W2059781616 hasAuthorship W2059781616A5051886378 @default.
- W2059781616 hasAuthorship W2059781616A5080179653 @default.
- W2059781616 hasConcept C126322002 @default.
- W2059781616 hasConcept C134018914 @default.
- W2059781616 hasConcept C172680121 @default.
- W2059781616 hasConcept C2778472085 @default.
- W2059781616 hasConcept C2779234561 @default.
- W2059781616 hasConcept C2779547902 @default.
- W2059781616 hasConcept C2779652256 @default.
- W2059781616 hasConcept C2779715522 @default.
- W2059781616 hasConcept C2780168142 @default.
- W2059781616 hasConcept C42407357 @default.
- W2059781616 hasConcept C529278444 @default.
- W2059781616 hasConcept C54355233 @default.
- W2059781616 hasConcept C551621295 @default.
- W2059781616 hasConcept C71924100 @default.
- W2059781616 hasConcept C86803240 @default.
- W2059781616 hasConceptScore W2059781616C126322002 @default.
- W2059781616 hasConceptScore W2059781616C134018914 @default.
- W2059781616 hasConceptScore W2059781616C172680121 @default.
- W2059781616 hasConceptScore W2059781616C2778472085 @default.
- W2059781616 hasConceptScore W2059781616C2779234561 @default.
- W2059781616 hasConceptScore W2059781616C2779547902 @default.
- W2059781616 hasConceptScore W2059781616C2779652256 @default.
- W2059781616 hasConceptScore W2059781616C2779715522 @default.
- W2059781616 hasConceptScore W2059781616C2780168142 @default.
- W2059781616 hasConceptScore W2059781616C42407357 @default.
- W2059781616 hasConceptScore W2059781616C529278444 @default.
- W2059781616 hasConceptScore W2059781616C54355233 @default.
- W2059781616 hasConceptScore W2059781616C551621295 @default.
- W2059781616 hasConceptScore W2059781616C71924100 @default.
- W2059781616 hasConceptScore W2059781616C86803240 @default.
- W2059781616 hasIssue "5" @default.
- W2059781616 hasLocation W20597816161 @default.
- W2059781616 hasLocation W20597816162 @default.
- W2059781616 hasOpenAccess W2059781616 @default.
- W2059781616 hasPrimaryLocation W20597816161 @default.
- W2059781616 hasRelatedWork W1973736968 @default.
- W2059781616 hasRelatedWork W1999345165 @default.
- W2059781616 hasRelatedWork W2019412495 @default.
- W2059781616 hasRelatedWork W2030127712 @default.
- W2059781616 hasRelatedWork W2030640518 @default.
- W2059781616 hasRelatedWork W2033615184 @default.
- W2059781616 hasRelatedWork W2034270961 @default.
- W2059781616 hasRelatedWork W2059781616 @default.
- W2059781616 hasRelatedWork W2114351292 @default.
- W2059781616 hasRelatedWork W2143178177 @default.
- W2059781616 hasVolume "25" @default.
- W2059781616 isParatext "false" @default.
- W2059781616 isRetracted "false" @default.
- W2059781616 magId "2059781616" @default.
- W2059781616 workType "article" @default.