FRINK Linked Data Fragments server

Matches in SemOpenAlex for { <https://semopenalex.org/work/W2059787600> ?p ?o ?g. }

• W2059787600 endingPage "1356" @default.
• W2059787600 startingPage "1349" @default.
• W2059787600 abstract "Severe injury can cause intestinal permeability through decreased expression of tight junction proteins, resulting in systemic inflammation. Activation of the parasympathetic nervous system after shock through vagal nerve stimulation is known to have potent anti-inflammatory effects; however, its effects on modulating intestinal barrier function are not fully understood. We postulated that vagal nerve stimulation improves intestinal barrier integrity after severe burn through an efferent signaling pathway, and is associated with improved expression and localization of the intestinal tight junction protein occludin.Male balb/c mice underwent right cervical vagal nerve stimulation for 10 minutes immediately before 30% total body surface area, full-thickness steam burn. In a separate arm, animals underwent abdominal vagotomy at the gastroesophageal junction before vagal nerve stimulation and burn. Intestinal barrier injury was assessed by permeability to 4 kDa FITC-dextran, histology, and changes in occludin expression using immunoblotting and confocal microscopy.Cervical vagal nerve stimulation decreased burn-induced intestinal permeability to FITC-dextran, returning intestinal permeability to sham levels. Vagal nerve stimulation before burn also improved gut histology and prevented burn-induced changes in occludin protein expression and localization. Abdominal vagotomy abrogated the protective effects of cervical vagal nerve stimulation before burn, resulting in gut permeability, histology, and occludin protein expression similar to burn alone.Vagal nerve stimulation performed before injury improves intestinal barrier integrity after severe burn through an efferent signaling pathway and is associated with improved tight junction protein expression." @default.
• W2059787600 created "2016-06-24" @default.
• W2059787600 creator A5001537127 @default.
• W2059787600 creator A5024786945 @default.
• W2059787600 creator A5037056131 @default.
• W2059787600 creator A5037539850 @default.
• W2059787600 creator A5037880923 @default.
• W2059787600 creator A5040209327 @default.
• W2059787600 creator A5041106533 @default.
• W2059787600 creator A5056467477 @default.
• W2059787600 creator A5060200337 @default.
• W2059787600 creator A5065355429 @default.
• W2059787600 date "2010-06-01" @default.
• W2059787600 modified "2023-10-04" @default.
• W2059787600 title "Efferent Vagal Nerve Stimulation Attenuates Gut Barrier Injury After Burn: Modulation of Intestinal Occludin Expression" @default.
• W2059787600 cites W1618627661 @default.
• W2059787600 cites W1985756708 @default.
• W2059787600 cites W1992040739 @default.
• W2059787600 cites W1995525413 @default.
• W2059787600 cites W2002797282 @default.
• W2059787600 cites W2006194008 @default.
• W2059787600 cites W2027848881 @default.
• W2059787600 cites W2029794340 @default.
• W2059787600 cites W2032123628 @default.
• W2059787600 cites W2032380005 @default.
• W2059787600 cites W2033002758 @default.
• W2059787600 cites W2036294223 @default.
• W2059787600 cites W2039901999 @default.
• W2059787600 cites W2044481171 @default.
• W2059787600 cites W2046775696 @default.
• W2059787600 cites W2050322036 @default.
• W2059787600 cites W2060470243 @default.
• W2059787600 cites W2069368135 @default.
• W2059787600 cites W2075850600 @default.
• W2059787600 cites W2082318361 @default.
• W2059787600 cites W2085062842 @default.
• W2059787600 cites W2086364254 @default.
• W2059787600 cites W2096579470 @default.
• W2059787600 cites W2100327483 @default.
• W2059787600 cites W2103831817 @default.
• W2059787600 cites W2126343491 @default.
• W2059787600 cites W2134354994 @default.
• W2059787600 cites W2148700019 @default.
• W2059787600 cites W2168682720 @default.
• W2059787600 cites W2313932305 @default.
• W2059787600 cites W4237282622 @default.
• W2059787600 doi "https://doi.org/10.1097/ta.0b013e3181dccea0" @default.
• W2059787600 hasPubMedCentralId "https://www.ncbi.nlm.nih.gov/pmc/articles/4251593" @default.
• W2059787600 hasPubMedId "https://pubmed.ncbi.nlm.nih.gov/20539179" @default.
• W2059787600 hasPublicationYear "2010" @default.
• W2059787600 type Work @default.
• W2059787600 sameAs 2059787600 @default.
• W2059787600 citedByCount "54" @default.
• W2059787600 countsByYear W20597876002012 @default.
• W2059787600 countsByYear W20597876002013 @default.
• W2059787600 countsByYear W20597876002014 @default.
• W2059787600 countsByYear W20597876002015 @default.
• W2059787600 countsByYear W20597876002016 @default.
• W2059787600 countsByYear W20597876002017 @default.
• W2059787600 countsByYear W20597876002018 @default.
• W2059787600 countsByYear W20597876002019 @default.
• W2059787600 countsByYear W20597876002020 @default.
• W2059787600 countsByYear W20597876002021 @default.
• W2059787600 countsByYear W20597876002022 @default.
• W2059787600 countsByYear W20597876002023 @default.
• W2059787600 crossrefType "journal-article" @default.
• W2059787600 hasAuthorship W2059787600A5001537127 @default.
• W2059787600 hasAuthorship W2059787600A5024786945 @default.
• W2059787600 hasAuthorship W2059787600A5037056131 @default.
• W2059787600 hasAuthorship W2059787600A5037539850 @default.
• W2059787600 hasAuthorship W2059787600A5037880923 @default.
• W2059787600 hasAuthorship W2059787600A5040209327 @default.
• W2059787600 hasAuthorship W2059787600A5041106533 @default.
• W2059787600 hasAuthorship W2059787600A5056467477 @default.
• W2059787600 hasAuthorship W2059787600A5060200337 @default.
• W2059787600 hasAuthorship W2059787600A5065355429 @default.
• W2059787600 hasBestOaLocation W20597876002 @default.
• W2059787600 hasConcept C126322002 @default.
• W2059787600 hasConcept C134018914 @default.
• W2059787600 hasConcept C142724271 @default.
• W2059787600 hasConcept C177779419 @default.
• W2059787600 hasConcept C24998067 @default.
• W2059787600 hasConcept C2775962179 @default.
• W2059787600 hasConcept C2776512019 @default.
• W2059787600 hasConcept C2778720886 @default.
• W2059787600 hasConcept C2779263132 @default.
• W2059787600 hasConcept C2780087125 @default.
• W2059787600 hasConcept C2781071285 @default.
• W2059787600 hasConcept C2781404750 @default.
• W2059787600 hasConcept C71924100 @default.
• W2059787600 hasConcept C86803240 @default.
• W2059787600 hasConcept C95444343 @default.
• W2059787600 hasConceptScore W2059787600C126322002 @default.
• W2059787600 hasConceptScore W2059787600C134018914 @default.
• W2059787600 hasConceptScore W2059787600C142724271 @default.
• W2059787600 hasConceptScore W2059787600C177779419 @default.
• W2059787600 hasConceptScore W2059787600C24998067 @default.
• W2059787600 hasConceptScore W2059787600C2775962179 @default.

• next