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- W2059794838 abstract "Maximum likelihood methods are used to estimate the birth prevalence, the age-at-diagnosis distribution, and the number of infants born with CF in Nova Scotia over a 20 year period. The data were taken from a registry of CF cases, and, because of the delayed onset of symptoms, some CF affected individuals were not diagnosed by the end of the study period. A goodness-of-fit test for assessing whether the age-at-diagnosis distribution is stable over the 20 years is provided. These methods could be applied equally well to data on any genetic disorder with delayed onset. Copyright © 2000 John Wiley & Sons, Ltd." @default.
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- W2059794838 date "2000-03-15" @default.
- W2059794838 modified "2023-10-18" @default.
- W2059794838 title "Retrospective estimation of the birth prevalence for delayed onset disorders: application to cystic fibrosis in Nova Scotia" @default.
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- W2059794838 doi "https://doi.org/10.1002/(sici)1097-0258(20000315)19:5<743::aid-sim338>3.0.co;2-f" @default.
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