Matches in SemOpenAlex for { <https://semopenalex.org/work/W2059826081> ?p ?o ?g. }
Showing items 1 to 93 of
93
with 100 items per page.
- W2059826081 endingPage "917" @default.
- W2059826081 startingPage "913" @default.
- W2059826081 abstract "Amanitins are toxins found in species of the mushroom genera Amanita, Lepiota and Galerina. Intoxication after ingestion of these mushrooms can be fatal with an estimated 20% of mortality rate. An early diagnosis is necessary in order to avoid invasive and expensive therapy and to improve patient's prognosis. In this paper, a Capillary Zone Electrophoresis method was developed and validated to determine alpha- and beta-amanitin in urine in less than 7 min using 5 mM, pH 10 borate buffer as background electrolyte. The separation conditions were: capillary: 75 microm I.D., 41 cm effective length, 48 cm total length, 25 degrees C, 20 KV and PDA detection at 214 nm. Sample treatment for analysis only required urine dilution in background electrolyte. The method was validated following established criteria and was found to be selective, linear in the range 5-100 ng/ml. Intra- and inter-day precision and accuracy were within required limits. Limit of detection (LOD) and limit of quantification (LOQ) were 1.5 and 5 ng/ml, respectively. Eight urine samples from suspected cases of intoxication with amanitins were analyzed after 2 years of storage at -20 degrees C, and beta-amanitin was determined in two samples with concentrations of 53 and 65 ng/ml, respectively. The method here described includes the use of non-aggressive reagents to the capillary or the system and is the first Capillary Electrophoresis method used to determine amanitins in clinical samples." @default.
- W2059826081 created "2016-06-24" @default.
- W2059826081 creator A5000684480 @default.
- W2059826081 creator A5002469246 @default.
- W2059826081 creator A5031323793 @default.
- W2059826081 creator A5033441342 @default.
- W2059826081 creator A5042379274 @default.
- W2059826081 creator A5056080517 @default.
- W2059826081 date "2008-08-01" @default.
- W2059826081 modified "2023-10-16" @default.
- W2059826081 title "Determination of α- and β-amanitin in clinical urine samples by Capillary Zone Electrophoresis" @default.
- W2059826081 cites W1937419779 @default.
- W2059826081 cites W1963972151 @default.
- W2059826081 cites W1965703074 @default.
- W2059826081 cites W1989755458 @default.
- W2059826081 cites W1999357009 @default.
- W2059826081 cites W2000633944 @default.
- W2059826081 cites W2006925806 @default.
- W2059826081 cites W2025982051 @default.
- W2059826081 cites W2026301420 @default.
- W2059826081 cites W2031470396 @default.
- W2059826081 cites W2073051773 @default.
- W2059826081 cites W2076634408 @default.
- W2059826081 cites W2079038753 @default.
- W2059826081 cites W2080358148 @default.
- W2059826081 cites W2081399033 @default.
- W2059826081 cites W2091625038 @default.
- W2059826081 cites W2095087032 @default.
- W2059826081 cites W2121864986 @default.
- W2059826081 cites W2129993651 @default.
- W2059826081 cites W2143465422 @default.
- W2059826081 cites W2165731875 @default.
- W2059826081 doi "https://doi.org/10.1016/j.jpba.2008.03.032" @default.
- W2059826081 hasPubMedId "https://pubmed.ncbi.nlm.nih.gov/18502601" @default.
- W2059826081 hasPublicationYear "2008" @default.
- W2059826081 type Work @default.
- W2059826081 sameAs 2059826081 @default.
- W2059826081 citedByCount "41" @default.
- W2059826081 countsByYear W20598260812012 @default.
- W2059826081 countsByYear W20598260812013 @default.
- W2059826081 countsByYear W20598260812014 @default.
- W2059826081 countsByYear W20598260812015 @default.
- W2059826081 countsByYear W20598260812016 @default.
- W2059826081 countsByYear W20598260812017 @default.
- W2059826081 countsByYear W20598260812018 @default.
- W2059826081 countsByYear W20598260812019 @default.
- W2059826081 countsByYear W20598260812020 @default.
- W2059826081 countsByYear W20598260812021 @default.
- W2059826081 countsByYear W20598260812022 @default.
- W2059826081 countsByYear W20598260812023 @default.
- W2059826081 crossrefType "journal-article" @default.
- W2059826081 hasAuthorship W2059826081A5000684480 @default.
- W2059826081 hasAuthorship W2059826081A5002469246 @default.
- W2059826081 hasAuthorship W2059826081A5031323793 @default.
- W2059826081 hasAuthorship W2059826081A5033441342 @default.
- W2059826081 hasAuthorship W2059826081A5042379274 @default.
- W2059826081 hasAuthorship W2059826081A5056080517 @default.
- W2059826081 hasConcept C10349863 @default.
- W2059826081 hasConcept C119128265 @default.
- W2059826081 hasConcept C185592680 @default.
- W2059826081 hasConcept C2780026642 @default.
- W2059826081 hasConcept C2900643 @default.
- W2059826081 hasConcept C43617362 @default.
- W2059826081 hasConcept C55493867 @default.
- W2059826081 hasConceptScore W2059826081C10349863 @default.
- W2059826081 hasConceptScore W2059826081C119128265 @default.
- W2059826081 hasConceptScore W2059826081C185592680 @default.
- W2059826081 hasConceptScore W2059826081C2780026642 @default.
- W2059826081 hasConceptScore W2059826081C2900643 @default.
- W2059826081 hasConceptScore W2059826081C43617362 @default.
- W2059826081 hasConceptScore W2059826081C55493867 @default.
- W2059826081 hasIssue "4-5" @default.
- W2059826081 hasLocation W20598260811 @default.
- W2059826081 hasLocation W20598260812 @default.
- W2059826081 hasOpenAccess W2059826081 @default.
- W2059826081 hasPrimaryLocation W20598260811 @default.
- W2059826081 hasRelatedWork W2017325659 @default.
- W2059826081 hasRelatedWork W2018283550 @default.
- W2059826081 hasRelatedWork W2023342487 @default.
- W2059826081 hasRelatedWork W2024274674 @default.
- W2059826081 hasRelatedWork W2347661148 @default.
- W2059826081 hasRelatedWork W2361247529 @default.
- W2059826081 hasRelatedWork W2372371902 @default.
- W2059826081 hasRelatedWork W2376356388 @default.
- W2059826081 hasRelatedWork W2409135126 @default.
- W2059826081 hasRelatedWork W2798043594 @default.
- W2059826081 hasVolume "47" @default.
- W2059826081 isParatext "false" @default.
- W2059826081 isRetracted "false" @default.
- W2059826081 magId "2059826081" @default.
- W2059826081 workType "article" @default.