FRINK Linked Data Fragments server

Matches in SemOpenAlex for { <https://semopenalex.org/work/W2059842777> ?p ?o ?g. }

• W2059842777 endingPage "546" @default.
• W2059842777 startingPage "546" @default.
• W2059842777 abstract "To the Editor: We read with great interest the comprehensive CME article by Dr Mutasim in the December 2004 issue of the Journal on the management of autoimmune bullous diseases. The author presented prednisone 1 mg/kg as the first drug to manage pemphigus vulgaris and suggested the addition of adjuvant treatment in case of nonresponse or adverse effects. Although the very high dosage of prednisolone suggested by Lever is no longer recommended, to the best of our knowledge there is not yet a general consensus based on well-designed controlled trials on the optimum dosage schedule of steroids. Ratman in the only relevant controlled trial, compared low-dose (60 mg) versus high-dose (120 mg) prednisolone, but no long-term advantage of the high-dose regimen was noted; his study had a small sample size (only 22 cases were enrolled, 3 of whom had pemphigus foliaceus). Pemphigus vulgaris has a relatively high prevalence in our country, and in our clinical experience we prefer to start with 2 mg/kg prednisolone combined with an adjuvant drug (eg, azathioprine, mycophenolate mofetil, or cyclophosphamide), especially in moderate to severe cases. The dosage is reduced by 30% after clinical response (usually after 10-14 days), and then tapered by 10 mg/week until 30 mg and slower afterwards. Doses greater than 1 mg/kg are not abandoned in other centers, too, and to the best of our knowledge, even many experts who prefer treating pemphigus with prednisolone 1 mg/kg increase the dosage in a stepwise manner in the case of a lack of response after 5 to 7 days. It appears that until a general consensus based on controlled trials is reached, it is more feasible to still recommend a range of 1 to 2 mg/kg for prednisolone dosage tailored by the clinical severity and the patient’s general health status in pemphigus vulgaris." @default.
• W2059842777 created "2016-06-24" @default.
• W2059842777 creator A5014368565 @default.
• W2059842777 creator A5047286483 @default.
• W2059842777 date "2005-09-01" @default.
• W2059842777 modified "2023-09-23" @default.
• W2059842777 title "Prednisolone dosage in pemphigus vulgaris" @default.
• W2059842777 cites W1964805892 @default.
• W2059842777 cites W1965962216 @default.
• W2059842777 cites W1970873810 @default.
• W2059842777 cites W1996773947 @default.
• W2059842777 cites W2006014608 @default.
• W2059842777 cites W2010044340 @default.
• W2059842777 cites W2012980289 @default.
• W2059842777 cites W2013361256 @default.
• W2059842777 cites W2019205814 @default.
• W2059842777 cites W2019808150 @default.
• W2059842777 cites W2034183668 @default.
• W2059842777 cites W2034585843 @default.
• W2059842777 cites W2053730359 @default.
• W2059842777 cites W2060359207 @default.
• W2059842777 cites W2065523538 @default.
• W2059842777 cites W2091442391 @default.
• W2059842777 cites W2105999475 @default.
• W2059842777 cites W2130925114 @default.
• W2059842777 cites W2137014627 @default.
• W2059842777 cites W2152976783 @default.
• W2059842777 cites W2153113150 @default.
• W2059842777 cites W2164533070 @default.
• W2059842777 cites W2185455986 @default.
• W2059842777 doi "https://doi.org/10.1016/j.jaad.2005.03.027" @default.
• W2059842777 hasPubMedId "https://pubmed.ncbi.nlm.nih.gov/16112385" @default.
• W2059842777 hasPublicationYear "2005" @default.
• W2059842777 type Work @default.
• W2059842777 sameAs 2059842777 @default.
• W2059842777 citedByCount "5" @default.
• W2059842777 countsByYear W20598427772013 @default.
• W2059842777 countsByYear W20598427772014 @default.
• W2059842777 countsByYear W20598427772019 @default.
• W2059842777 crossrefType "journal-article" @default.
• W2059842777 hasAuthorship W2059842777A5014368565 @default.
• W2059842777 hasAuthorship W2059842777A5047286483 @default.
• W2059842777 hasConcept C126322002 @default.
• W2059842777 hasConcept C16005928 @default.
• W2059842777 hasConcept C2776715498 @default.
• W2059842777 hasConcept C2781313415 @default.
• W2059842777 hasConcept C2781327288 @default.
• W2059842777 hasConcept C71924100 @default.
• W2059842777 hasConceptScore W2059842777C126322002 @default.
• W2059842777 hasConceptScore W2059842777C16005928 @default.
• W2059842777 hasConceptScore W2059842777C2776715498 @default.
• W2059842777 hasConceptScore W2059842777C2781313415 @default.
• W2059842777 hasConceptScore W2059842777C2781327288 @default.
• W2059842777 hasConceptScore W2059842777C71924100 @default.
• W2059842777 hasIssue "3" @default.
• W2059842777 hasLocation W20598427771 @default.
• W2059842777 hasLocation W20598427772 @default.
• W2059842777 hasOpenAccess W2059842777 @default.
• W2059842777 hasPrimaryLocation W20598427771 @default.
• W2059842777 hasRelatedWork W154449998 @default.
• W2059842777 hasRelatedWork W1983681111 @default.
• W2059842777 hasRelatedWork W2011564346 @default.
• W2059842777 hasRelatedWork W2398216003 @default.
• W2059842777 hasRelatedWork W2467696209 @default.
• W2059842777 hasRelatedWork W2947466769 @default.
• W2059842777 hasRelatedWork W4200324425 @default.
• W2059842777 hasRelatedWork W4320491243 @default.
• W2059842777 hasRelatedWork W2549144158 @default.
• W2059842777 hasRelatedWork W3121915352 @default.
• W2059842777 hasVolume "53" @default.
• W2059842777 isParatext "false" @default.
• W2059842777 isRetracted "false" @default.
• W2059842777 magId "2059842777" @default.
• W2059842777 workType "article" @default.