FRINK Linked Data Fragments server

Matches in SemOpenAlex for { <https://semopenalex.org/work/W2059884070> ?p ?o ?g. }

• W2059884070 endingPage "33" @default.
• W2059884070 startingPage "1" @default.
• W2059884070 abstract "Abstract Antibiotic resistance is increasing at a rate that far exceeds the pace of new development of drugs. Antimicrobial peptides, both synthetic and from natural sources, have raised interest as pathogens become resistant against conventional antibiotics. Indeed, one of the major strengths of this class of molecules is their ability to kill multidrug-resistant bacteria. Antimicrobial peptides are relatively small (6 to 100 aminoacids), amphipathic molecules of variable length, sequence and structure with activity against a wide range of microorganisms including bacteria, protozoa, yeast, fungi, viruses and even tumor cells. They usually act through relatively non-specific mechanisms resulting in membranolytic activity but they can also stimulate the innate immune response. Several peptides have already entered pre-clinical and clinical trials for the treatment of catheter site infections, cystic fibrosis, acne, wound healing and patients undergoing stem cell transplantation. We review the advantages of these molecules in clinical applications, their disadvantages including their low in vivo stability, high costs of production and the strategies for their discovery and optimization." @default.
• W2059884070 created "2016-06-24" @default.
• W2059884070 creator A5004760763 @default.
• W2059884070 creator A5024113661 @default.
• W2059884070 creator A5041008278 @default.
• W2059884070 date "2007-03-01" @default.
• W2059884070 modified "2023-10-10" @default.
• W2059884070 title "Antimicrobial peptides: an overview of a promising class of therapeutics" @default.
• W2059884070 cites W104835181 @default.
• W2059884070 cites W108623303 @default.
• W2059884070 cites W1484855411 @default.
• W2059884070 cites W1529044909 @default.
• W2059884070 cites W1539072848 @default.
• W2059884070 cites W1547998655 @default.
• W2059884070 cites W1557782384 @default.
• W2059884070 cites W1847489898 @default.
• W2059884070 cites W1923665285 @default.
• W2059884070 cites W1944553966 @default.
• W2059884070 cites W1963584412 @default.
• W2059884070 cites W1963606380 @default.
• W2059884070 cites W1966869152 @default.
• W2059884070 cites W1967476094 @default.
• W2059884070 cites W1967712898 @default.
• W2059884070 cites W1969711244 @default.
• W2059884070 cites W1974487582 @default.
• W2059884070 cites W1974768174 @default.
• W2059884070 cites W1976301815 @default.
• W2059884070 cites W1979420044 @default.
• W2059884070 cites W1981255596 @default.
• W2059884070 cites W1986159104 @default.
• W2059884070 cites W1988230764 @default.
• W2059884070 cites W1988441448 @default.
• W2059884070 cites W1989998611 @default.
• W2059884070 cites W1992259275 @default.
• W2059884070 cites W1992331668 @default.
• W2059884070 cites W1992603413 @default.
• W2059884070 cites W1992753858 @default.
• W2059884070 cites W1995412010 @default.
• W2059884070 cites W1996359284 @default.
• W2059884070 cites W1996723116 @default.
• W2059884070 cites W1997152791 @default.
• W2059884070 cites W1998601156 @default.
• W2059884070 cites W2001018320 @default.
• W2059884070 cites W2001784844 @default.
• W2059884070 cites W2002114807 @default.
• W2059884070 cites W2003797537 @default.
• W2059884070 cites W2003897459 @default.
• W2059884070 cites W2004373761 @default.
• W2059884070 cites W2007292590 @default.
• W2059884070 cites W2007744639 @default.
• W2059884070 cites W2008438580 @default.
• W2059884070 cites W2008899662 @default.
• W2059884070 cites W2009440109 @default.
• W2059884070 cites W2009592988 @default.
• W2059884070 cites W2011615074 @default.
• W2059884070 cites W2012815507 @default.
• W2059884070 cites W2013580058 @default.
• W2059884070 cites W2013674343 @default.
• W2059884070 cites W2015424604 @default.
• W2059884070 cites W2020154280 @default.
• W2059884070 cites W2020755269 @default.
• W2059884070 cites W2020790969 @default.
• W2059884070 cites W2021413161 @default.
• W2059884070 cites W2021800929 @default.
• W2059884070 cites W2022998979 @default.
• W2059884070 cites W2024043943 @default.
• W2059884070 cites W2024602938 @default.
• W2059884070 cites W2028869026 @default.
• W2059884070 cites W2028903194 @default.
• W2059884070 cites W2030394100 @default.
• W2059884070 cites W2032284161 @default.
• W2059884070 cites W2034517648 @default.
• W2059884070 cites W2034817631 @default.
• W2059884070 cites W2038208689 @default.
• W2059884070 cites W2039694750 @default.
• W2059884070 cites W2045435680 @default.
• W2059884070 cites W2047795757 @default.
• W2059884070 cites W2049094183 @default.
• W2059884070 cites W2052186635 @default.
• W2059884070 cites W2053770622 @default.
• W2059884070 cites W2054421242 @default.
• W2059884070 cites W2054602599 @default.
• W2059884070 cites W2055856930 @default.
• W2059884070 cites W2056039068 @default.
• W2059884070 cites W2057581357 @default.
• W2059884070 cites W2058910840 @default.
• W2059884070 cites W2060240716 @default.
• W2059884070 cites W2061910359 @default.
• W2059884070 cites W2063116767 @default.
• W2059884070 cites W2065067981 @default.
• W2059884070 cites W2067907816 @default.
• W2059884070 cites W2067962729 @default.
• W2059884070 cites W2068220342 @default.
• W2059884070 cites W2068354047 @default.
• W2059884070 cites W2068434462 @default.
• W2059884070 cites W2073066899 @default.
• W2059884070 cites W2073215039 @default.
• W2059884070 cites W2074664772 @default.

• next