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• W2059888146 abstract "As substance use disorders (SUD) are common in schizophrenia patients, we tested the hypothesis that comorbid patients (SUD[+]) have more positive vs. negative symptoms than non-comorbid (SUD[-]) patients. From reports identified by literature-searching we compared Positive and Negative Syndrome Scale (PANSS) ratings in schizophrenia patients with and without SUD using meta-analytic methods. Among 9 comparisons (N = 725 subjects), SUD[+] patients were more often men, and abused alcohol > cannabis > cocaine. SUD[+] patients had very significantly higher PANSS-positive, and lower PANSS-negative scores. Comorbid SUD in schizophrenia patients was associated with male sex and higher PANSS positive to lower negative scores. Cause–effect relationships remain to be clarified." @default.
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• W2059888146 date "2006-09-01" @default.
• W2059888146 modified "2023-10-16" @default.
• W2059888146 title "Comorbid substance-use in schizophrenia: Relation to positive and negative symptoms" @default.
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• W2059888146 doi "https://doi.org/10.1016/j.schres.2006.04.004" @default.
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