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- W2059892479 abstract "Renal function was studied in children with congenital obstructive uropathy, and followed for 3 to 13 years after reconstructive surgery. Glomerular filtration rate (GFR) was assessed by the clearance of endogenous creatinine or inulin. Effective renal plasma flow was assessed by the clearance of PAH. In 14 out of 28 patients, reconstructive surgery was performed during the first year of life. Urines were subsequently kept sterile. Three different patterns of evolution could be observed after repair of obstructive uropathy : 1) GFR remained normal and stable in all patients with a normal renal function at the time of surgery. 2) Long-term prognosis was good in those children with a moderate decrease in GFR (less than 40%), when surgical treatment was performed during the first year of life. 3) A progressive deterioration of renal function was observed in patients with a marked decrease in GFR (more than 40%) at the time of surgery, and/or when surgical treatment was performed after 12 months of life." @default.
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- W2059892479 date "1974-11-01" @default.
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- W2059892479 title "A follow-up study of renal function in post-obstructive nephropathy" @default.
- W2059892479 doi "https://doi.org/10.1203/00006450-197411000-00018" @default.
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