Matches in SemOpenAlex for { <https://semopenalex.org/work/W2059905263> ?p ?o ?g. }
Showing items 1 to 92 of
92
with 100 items per page.
- W2059905263 endingPage "245" @default.
- W2059905263 startingPage "237" @default.
- W2059905263 abstract "The beige mouse (bg/bg) is an analogue of the Chediak-Higashi syndrome (CHS) in man. The disorder is characterised by the presence of enlarged cytoplasmic granules, said to be lysosomes, in many cell types. The present report describes giant lysosomes defined as lysosomes greater than 1.0 micrometers in diameter, in osteoclasts of beige mice. The giant lysosomes contained both acid phosphatase and aryl sulphatase and were present in osteoclasts of beige mice aged from at least 4 days to 3 months. There is some evidence that the giant lysosomes form by fusion of smaller structures. Since giant lysosomes were also seen in osteoclasts from mouse strains not suffering from CHS, e.g., CBA mice, a quantitative survey was carried out. It was shown that osteoclasts from beige mice aged from 4 days to 3 months contain significantly increased numbers of giant lysosomes when compared with osteoclasts from CBA mice and CBAXbg/bg F1 hybrids. The giant lysosomes of the beige mouse osteoclast are currently being used as cytoplasmic markers in experiments on the cell of origin of the osteoclast." @default.
- W2059905263 created "2016-06-24" @default.
- W2059905263 creator A5008346073 @default.
- W2059905263 creator A5010078690 @default.
- W2059905263 creator A5017367591 @default.
- W2059905263 date "1980-04-01" @default.
- W2059905263 modified "2023-09-25" @default.
- W2059905263 title "Giant lysosomes, a cytoplasmic marker in osteoclasts of beige mice" @default.
- W2059905263 cites W1475713056 @default.
- W2059905263 cites W1537396858 @default.
- W2059905263 cites W1982737414 @default.
- W2059905263 cites W1997959817 @default.
- W2059905263 cites W2007704417 @default.
- W2059905263 cites W2012600477 @default.
- W2059905263 cites W2015052084 @default.
- W2059905263 cites W2018668472 @default.
- W2059905263 cites W2033801664 @default.
- W2059905263 cites W2068595115 @default.
- W2059905263 cites W2093617753 @default.
- W2059905263 cites W2108192721 @default.
- W2059905263 cites W2109401564 @default.
- W2059905263 cites W2109476664 @default.
- W2059905263 cites W2138948114 @default.
- W2059905263 cites W2170162094 @default.
- W2059905263 cites W2211749279 @default.
- W2059905263 cites W2499025676 @default.
- W2059905263 cites W2886343980 @default.
- W2059905263 cites W55200214 @default.
- W2059905263 cites W56708359 @default.
- W2059905263 cites W2121546449 @default.
- W2059905263 doi "https://doi.org/10.1002/path.1711300405" @default.
- W2059905263 hasPubMedId "https://pubmed.ncbi.nlm.nih.gov/7391859" @default.
- W2059905263 hasPublicationYear "1980" @default.
- W2059905263 type Work @default.
- W2059905263 sameAs 2059905263 @default.
- W2059905263 citedByCount "24" @default.
- W2059905263 crossrefType "journal-article" @default.
- W2059905263 hasAuthorship W2059905263A5008346073 @default.
- W2059905263 hasAuthorship W2059905263A5010078690 @default.
- W2059905263 hasAuthorship W2059905263A5017367591 @default.
- W2059905263 hasConcept C136403682 @default.
- W2059905263 hasConcept C153911025 @default.
- W2059905263 hasConcept C181199279 @default.
- W2059905263 hasConcept C190062978 @default.
- W2059905263 hasConcept C202751555 @default.
- W2059905263 hasConcept C203014093 @default.
- W2059905263 hasConcept C21547065 @default.
- W2059905263 hasConcept C2776033226 @default.
- W2059905263 hasConcept C2776070026 @default.
- W2059905263 hasConcept C2780216420 @default.
- W2059905263 hasConcept C54355233 @default.
- W2059905263 hasConcept C55493867 @default.
- W2059905263 hasConcept C77076574 @default.
- W2059905263 hasConcept C86803240 @default.
- W2059905263 hasConcept C95444343 @default.
- W2059905263 hasConceptScore W2059905263C136403682 @default.
- W2059905263 hasConceptScore W2059905263C153911025 @default.
- W2059905263 hasConceptScore W2059905263C181199279 @default.
- W2059905263 hasConceptScore W2059905263C190062978 @default.
- W2059905263 hasConceptScore W2059905263C202751555 @default.
- W2059905263 hasConceptScore W2059905263C203014093 @default.
- W2059905263 hasConceptScore W2059905263C21547065 @default.
- W2059905263 hasConceptScore W2059905263C2776033226 @default.
- W2059905263 hasConceptScore W2059905263C2776070026 @default.
- W2059905263 hasConceptScore W2059905263C2780216420 @default.
- W2059905263 hasConceptScore W2059905263C54355233 @default.
- W2059905263 hasConceptScore W2059905263C55493867 @default.
- W2059905263 hasConceptScore W2059905263C77076574 @default.
- W2059905263 hasConceptScore W2059905263C86803240 @default.
- W2059905263 hasConceptScore W2059905263C95444343 @default.
- W2059905263 hasIssue "4" @default.
- W2059905263 hasLocation W20599052631 @default.
- W2059905263 hasLocation W20599052632 @default.
- W2059905263 hasOpenAccess W2059905263 @default.
- W2059905263 hasPrimaryLocation W20599052631 @default.
- W2059905263 hasRelatedWork W130212105 @default.
- W2059905263 hasRelatedWork W1944271847 @default.
- W2059905263 hasRelatedWork W1977799214 @default.
- W2059905263 hasRelatedWork W1990848888 @default.
- W2059905263 hasRelatedWork W2045051521 @default.
- W2059905263 hasRelatedWork W2050047645 @default.
- W2059905263 hasRelatedWork W2059905263 @default.
- W2059905263 hasRelatedWork W2162223306 @default.
- W2059905263 hasRelatedWork W2416426821 @default.
- W2059905263 hasRelatedWork W2430074393 @default.
- W2059905263 hasVolume "130" @default.
- W2059905263 isParatext "false" @default.
- W2059905263 isRetracted "false" @default.
- W2059905263 magId "2059905263" @default.
- W2059905263 workType "article" @default.