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- W2059910088 abstract "We have assessed the relationship between indices of adiposity and antibody titers to Hsp-27 in healthy subjects. Two-hundred and fifty subjects were studied, including 50 normal-weight subjects (body-mass-index (BMI) ˂25 kg/m2), 100 overweight subjects (BMI 25 to ˂30 kg/m2) (n = 100) and 100 obese subjects (BMI ≥ 30 kg/m2). Anti-Hsp27-antibody levels in obese subjects were [0.34 (0.20–0.39) absorbency unit], being significantly higher than overweight and normal-weight groups (P < 0.05). Anti-Hsp27-antibody levels in overweight subjects [0.29 (0.15–0.34) absorbency unit] were statistically higher than controls [0.18 (0.10–0.23) absorbency unit] (P < 0.05). High anti-Hsp-27-antibody levels in obese-subjects without established coronary disease may be related to a heightened state of immunoactivation associated with obesity." @default.
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- W2059910088 date "2012-01-01" @default.
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- W2059910088 title "Association between indices of body mass and antibody titers to heat-shock protein-27 in healthy subjects" @default.
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- W2059910088 doi "https://doi.org/10.1016/j.clinbiochem.2011.09.022" @default.
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