FRINK Linked Data Fragments server

Matches in SemOpenAlex for { <https://semopenalex.org/work/W2059911596> ?p ?o ?g. }

• W2059911596 endingPage "244" @default.
• W2059911596 startingPage "238" @default.
• W2059911596 abstract "Non-convulsive status epilepticus (NCSE) is characterized by continuous or recurrent, generalized or focal epileptiform activity on the electroencephalogram and diverse clinical symptoms with alterations of mental state and vigilance. NCSE is not rare but certainly under diagnosed. There is some debate about how aggressive NCSE should be treated, as high dose anticonvulsants maybe partially responsible for the morbidity and mortality of patients with NCSE. We hypothesized that levetiracetam (LEV) as a well tolerated, highly effective new anticonvulsant, may be a safe treatment option. We retrospectively analyzed all (8) patients with NCSE who received levetiracetam from our database, compared with 11 patients with NCSE treated with conventional intravenous status medication as controls. These eight patients showed a marked clinical improvement with final cessation of ictal EEG-activity and clinical symptoms of NCSE after initiation of LEV within 3 days (mean 1.5 days). The response to conventional treatment was similarly effective but there were severe side effects whereas no relevant side effects in the LEV-treated group were noticed. A long-term follow up (6–36 months from discharge) revealed six patients with a persisting reduction in seizure frequency on medication with LEV. One patient changed the anticonvulsive medication because of inefficacy and one died from other causes than epilepsy 2 months after discharge from hospital. We found no significant differences in hospitalisation time, time in intensive care unit and outcome between the LEV group and the control group. This retrospectively acquired data suggests that LEV may be a well tolerated, effective treatment option in NCSE. This highlights the need for a prospective controlled study to further elucidate the utility of LEV in the treatment of NCSE, particularly as an intravenous formulation is now available." @default.
• W2059911596 created "2016-06-24" @default.
• W2059911596 creator A5013080680 @default.
• W2059911596 creator A5016603751 @default.
• W2059911596 creator A5028176182 @default.
• W2059911596 creator A5055095906 @default.
• W2059911596 creator A5070787668 @default.
• W2059911596 date "2007-03-01" @default.
• W2059911596 modified "2023-09-23" @default.
• W2059911596 title "Levetiracetam as a treatment option in non-convulsive status epilepticus" @default.
• W2059911596 cites W1970167469 @default.
• W2059911596 cites W1975418138 @default.
• W2059911596 cites W1978460142 @default.
• W2059911596 cites W1979558709 @default.
• W2059911596 cites W1983562301 @default.
• W2059911596 cites W1985474099 @default.
• W2059911596 cites W1997544686 @default.
• W2059911596 cites W1997939068 @default.
• W2059911596 cites W2000899854 @default.
• W2059911596 cites W2021017859 @default.
• W2059911596 cites W2025490080 @default.
• W2059911596 cites W2027485323 @default.
• W2059911596 cites W2032555999 @default.
• W2059911596 cites W2034323512 @default.
• W2059911596 cites W2040459669 @default.
• W2059911596 cites W2049354071 @default.
• W2059911596 cites W2052869629 @default.
• W2059911596 cites W2056821940 @default.
• W2059911596 cites W2057157397 @default.
• W2059911596 cites W2057603779 @default.
• W2059911596 cites W2061232753 @default.
• W2059911596 cites W2066952531 @default.
• W2059911596 cites W2068305426 @default.
• W2059911596 cites W2070541489 @default.
• W2059911596 cites W2071633231 @default.
• W2059911596 cites W2092739453 @default.
• W2059911596 cites W2123177504 @default.
• W2059911596 cites W2160038182 @default.
• W2059911596 cites W2162474866 @default.
• W2059911596 cites W2168143783 @default.
• W2059911596 cites W4237036841 @default.
• W2059911596 cites W4252893597 @default.
• W2059911596 doi "https://doi.org/10.1016/j.eplepsyres.2006.10.011" @default.
• W2059911596 hasPubMedId "https://pubmed.ncbi.nlm.nih.gov/17161587" @default.
• W2059911596 hasPublicationYear "2007" @default.
• W2059911596 type Work @default.
• W2059911596 sameAs 2059911596 @default.
• W2059911596 citedByCount "72" @default.
• W2059911596 countsByYear W20599115962012 @default.
• W2059911596 countsByYear W20599115962013 @default.
• W2059911596 countsByYear W20599115962014 @default.
• W2059911596 countsByYear W20599115962015 @default.
• W2059911596 countsByYear W20599115962016 @default.
• W2059911596 countsByYear W20599115962017 @default.
• W2059911596 countsByYear W20599115962020 @default.
• W2059911596 countsByYear W20599115962021 @default.
• W2059911596 countsByYear W20599115962022 @default.
• W2059911596 crossrefType "journal-article" @default.
• W2059911596 hasAuthorship W2059911596A5013080680 @default.
• W2059911596 hasAuthorship W2059911596A5016603751 @default.
• W2059911596 hasAuthorship W2059911596A5028176182 @default.
• W2059911596 hasAuthorship W2059911596A5055095906 @default.
• W2059911596 hasAuthorship W2059911596A5070787668 @default.
• W2059911596 hasConcept C118552586 @default.
• W2059911596 hasConcept C126322002 @default.
• W2059911596 hasConcept C167135981 @default.
• W2059911596 hasConcept C17755696 @default.
• W2059911596 hasConcept C187212893 @default.
• W2059911596 hasConcept C2775858608 @default.
• W2059911596 hasConcept C2776376669 @default.
• W2059911596 hasConcept C2777332695 @default.
• W2059911596 hasConcept C2777341932 @default.
• W2059911596 hasConcept C2777496795 @default.
• W2059911596 hasConcept C2778186239 @default.
• W2059911596 hasConcept C42219234 @default.
• W2059911596 hasConcept C71924100 @default.
• W2059911596 hasConceptScore W2059911596C118552586 @default.
• W2059911596 hasConceptScore W2059911596C126322002 @default.
• W2059911596 hasConceptScore W2059911596C167135981 @default.
• W2059911596 hasConceptScore W2059911596C17755696 @default.
• W2059911596 hasConceptScore W2059911596C187212893 @default.
• W2059911596 hasConceptScore W2059911596C2775858608 @default.
• W2059911596 hasConceptScore W2059911596C2776376669 @default.
• W2059911596 hasConceptScore W2059911596C2777332695 @default.
• W2059911596 hasConceptScore W2059911596C2777341932 @default.
• W2059911596 hasConceptScore W2059911596C2777496795 @default.
• W2059911596 hasConceptScore W2059911596C2778186239 @default.
• W2059911596 hasConceptScore W2059911596C42219234 @default.
• W2059911596 hasConceptScore W2059911596C71924100 @default.
• W2059911596 hasIssue "3" @default.
• W2059911596 hasLocation W20599115961 @default.
• W2059911596 hasLocation W20599115962 @default.
• W2059911596 hasOpenAccess W2059911596 @default.
• W2059911596 hasPrimaryLocation W20599115961 @default.
• W2059911596 hasRelatedWork W1985056740 @default.
• W2059911596 hasRelatedWork W1986230450 @default.
• W2059911596 hasRelatedWork W2000899854 @default.
• W2059911596 hasRelatedWork W2002328119 @default.

• next