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- W2059925101 abstract "Summary Gastric freezing was performed on dogs and function studies were done prior to the freezing procedure and 2 weeks afterwards, at which time the dogs were sacrificed and their stomachs examined histologically. In another group of dogs the gastric freezing was performed and the dogs were sacrificed 1 month later. It was found that there was a statistically significant decrease of volume, but that the total free acidity and pH were not altered 2 weeks after the gastric freezing. The lack of inhibition of gastric acidity may be caused by the injury of parietal cells limited to the focal areas of the gastric mucosa. In focal areas the parietal and chief cells did not regenerate within 2 weeks. Temperature control was best achieved through the use of the Temtrol instrument and there was less damage to the gastric mucosa with the use of this type of apparatus for freezing. Extremely low freezing temperatures and lower weights of the animals were more frequently associated with the presence of ulcers. Application of pitressin inhibited the incidence of various gastric lesions. No lesions were found in dogs sacrificed 1 month after gastric freezing. It is suggested that the gastric freezing procedure should be modified to induce more extensive selective parietal cell damage in order to achieve inhibition of the gastric acidity." @default.
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- W2059925101 date "1968-05-01" @default.
- W2059925101 modified "2023-09-26" @default.
- W2059925101 title "Alterations during the repair of injury induced by gastric freezing" @default.
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- W2059925101 doi "https://doi.org/10.1016/s0011-2240(68)80129-4" @default.
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