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- W2059939007 abstract "A series of 3,3′-pyrrolidonyl spirooxindole derivatives have been synthesized in good yields from the cascade Knoevenagel–Michael–cyclization multicomponent reaction of isatin, malononitrile and α-isothiocyanato imide in the presence of a catalytic amount of triethylamine “on water” assisted with ultrasonic irradiation. The advantages of this method include high efficiency, mild reaction conditions and environmentally benign reagents. The current process provides a simple and green method for creating diversity-oriented syntheses of this intriguing class of compounds with potential biological activities." @default.
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- W2059939007 date "2013-01-01" @default.
- W2059939007 modified "2023-10-06" @default.
- W2059939007 title "An environmentally benign approach for the synthesis of 3,3′-pyrrolidonyl spirooxindole derivatives via a cascade Knoevenagel–Michael–cyclization multicomponent reaction" @default.
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- W2059939007 doi "https://doi.org/10.1039/c3ra44119a" @default.
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