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- W2059944356 abstract "The receptor tyrosine phosphatases DPTP69D and DPTP99A are expressed on motor axons in Drosophila embryos. In mutant embryos lacking DPTP69D protein, motor neuron growth cones stop growing before reaching their muscle targets, or follow incorrect pathways that bypass these muscles. Mutant embryos lacking DPTP99A are indistinguishable from wild type. Motor axon defects in dptp69D dptp99A double mutant embryos, however, are much more severe than in embryos lacking only DPTP69D. Our results demonstrate that DPTP69D and DPTP99A are required for motor axon guidance and that they have partially redundant functions during development of the neuro-muscular system." @default.
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- W2059944356 date "1996-02-01" @default.
- W2059944356 modified "2023-10-18" @default.
- W2059944356 title "Receptor Tyrosine Phosphatases Are Required for Motor Axon Guidance in the Drosophila Embryo" @default.
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- W2059944356 doi "https://doi.org/10.1016/s0092-8674(00)81035-1" @default.
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