FRINK Linked Data Fragments server

Matches in SemOpenAlex for { <https://semopenalex.org/work/W2060036041> ?p ?o ?g. }

• W2060036041 endingPage "512" @default.
• W2060036041 startingPage "506" @default.
• W2060036041 abstract "To ascertain the prevalence and severity of phenytoin-induced gingival enlargement (PIGE) as well as the relationship between PIGE and risk factors.An outpatient population of patients on phenytoin treatment and attending the epilepsy clinic at Prince Mshiyeni Memorial Hospital (PMMH) in Durban, South Africa, was requested to participate. A structured questionnaire was used to collect data on patients' demographics, social habits (e.g., drinking and smoking), dental and oral hygiene practices and medication history. Gingival enlargement, dental plaque and gingival bleeding was also measured to assess gingival health. Venous blood was collected for serum folate and phenytoin serum levels measurements. A regression analyses was then undertaken to ascertain the association between PIGE and the risk factors. Factors tested for correlation were serum phenytoin and folate levels, age, bacterial plaque, gingival inflammation, toothbrushing, smoking and alcohol consumption. The association between PIGE and the risk factors was assessed either individually, i.e., as a single entity or in combination--multifactorially.Of the 134 patients studied, 62% had PIGE scores > or = 1, while 8% had a PIGE score of zero. With the exception of plaque, which showed a moderate association with PIGE (r=0.4), no other factor on its own was statistically significantly related to PIGE. In the multiple linear regression analysis, factors which on their own did not have a strong influence became more important. Bacterial plaque (p=0.0001), younger age (p=0.01) and higher free serum phenytoin levels (p= 0.03), were associated with PIGE. Although known to be associated with periodontal diseases, smoking and alcohol, (p=0.03 and p=0.04 respectively), appeared to give some protection against PIGE.Risk factors associated with PIGE may have a synergistic effect. Bacterial plaque, however, appears the most important determinant of PIGE severity. This latter finding emphasises the importance of instituting a preventive plaque-control programme, particularly in young patients on phenytoin therapy." @default.
• W2060036041 created "2016-06-24" @default.
• W2060036041 creator A5008855655 @default.
• W2060036041 creator A5047903492 @default.
• W2060036041 creator A5053130334 @default.
• W2060036041 creator A5073525281 @default.
• W2060036041 creator A5078990811 @default.
• W2060036041 creator A5080773461 @default.
• W2060036041 date "2000-07-01" @default.
• W2060036041 modified "2023-09-25" @default.
• W2060036041 title "Factors influencing phenytoin-induced gingival enlargement" @default.
• W2060036041 doi "https://doi.org/10.1034/j.1600-051x.2000.027007506.x" @default.
• W2060036041 hasPubMedId "https://pubmed.ncbi.nlm.nih.gov/10914892" @default.
• W2060036041 hasPublicationYear "2000" @default.
• W2060036041 type Work @default.
• W2060036041 sameAs 2060036041 @default.
• W2060036041 citedByCount "69" @default.
• W2060036041 countsByYear W20600360412012 @default.
• W2060036041 countsByYear W20600360412013 @default.
• W2060036041 countsByYear W20600360412014 @default.
• W2060036041 countsByYear W20600360412015 @default.
• W2060036041 countsByYear W20600360412016 @default.
• W2060036041 countsByYear W20600360412017 @default.
• W2060036041 countsByYear W20600360412018 @default.
• W2060036041 countsByYear W20600360412019 @default.
• W2060036041 countsByYear W20600360412020 @default.
• W2060036041 countsByYear W20600360412021 @default.
• W2060036041 countsByYear W20600360412022 @default.
• W2060036041 crossrefType "journal-article" @default.
• W2060036041 hasAuthorship W2060036041A5008855655 @default.
• W2060036041 hasAuthorship W2060036041A5047903492 @default.
• W2060036041 hasAuthorship W2060036041A5053130334 @default.
• W2060036041 hasAuthorship W2060036041A5073525281 @default.
• W2060036041 hasAuthorship W2060036041A5078990811 @default.
• W2060036041 hasAuthorship W2060036041A5080773461 @default.
• W2060036041 hasConcept C118552586 @default.
• W2060036041 hasConcept C126322002 @default.
• W2060036041 hasConcept C199343813 @default.
• W2060036041 hasConcept C2778186239 @default.
• W2060036041 hasConcept C2778337148 @default.
• W2060036041 hasConcept C2780090536 @default.
• W2060036041 hasConcept C2908647359 @default.
• W2060036041 hasConcept C515851188 @default.
• W2060036041 hasConcept C71924100 @default.
• W2060036041 hasConcept C99454951 @default.
• W2060036041 hasConceptScore W2060036041C118552586 @default.
• W2060036041 hasConceptScore W2060036041C126322002 @default.
• W2060036041 hasConceptScore W2060036041C199343813 @default.
• W2060036041 hasConceptScore W2060036041C2778186239 @default.
• W2060036041 hasConceptScore W2060036041C2778337148 @default.
• W2060036041 hasConceptScore W2060036041C2780090536 @default.
• W2060036041 hasConceptScore W2060036041C2908647359 @default.
• W2060036041 hasConceptScore W2060036041C515851188 @default.
• W2060036041 hasConceptScore W2060036041C71924100 @default.
• W2060036041 hasConceptScore W2060036041C99454951 @default.
• W2060036041 hasIssue "7" @default.
• W2060036041 hasLocation W20600360411 @default.
• W2060036041 hasLocation W20600360412 @default.
• W2060036041 hasOpenAccess W2060036041 @default.
• W2060036041 hasPrimaryLocation W20600360411 @default.
• W2060036041 hasRelatedWork W1577196318 @default.
• W2060036041 hasRelatedWork W2046505707 @default.
• W2060036041 hasRelatedWork W2051516053 @default.
• W2060036041 hasRelatedWork W2062823147 @default.
• W2060036041 hasRelatedWork W2134138405 @default.
• W2060036041 hasRelatedWork W2280445319 @default.
• W2060036041 hasRelatedWork W2419117908 @default.
• W2060036041 hasRelatedWork W2595456235 @default.
• W2060036041 hasRelatedWork W2761929328 @default.
• W2060036041 hasRelatedWork W2922264041 @default.
• W2060036041 hasVolume "27" @default.
• W2060036041 isParatext "false" @default.
• W2060036041 isRetracted "false" @default.
• W2060036041 magId "2060036041" @default.
• W2060036041 workType "article" @default.