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- W2060036095 abstract "The use of antibodies or antibody fragments for targeting tumors (either for tumor imaging or as carriers for drugs or toxins), has encountered problems of clearance, and non-specific or inefficient binding in clinical trials. A novel approach, linking two antibody variable fragments (Fvs), with a short peptide to generate a continuous polypeptide chain, may be able to overcome some of these problems. Since these single chain antibody variable regions (scFvs), are transcribed from constructed 'genes', large-scale production in, for example, E. coli, should be straightforward." @default.
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- W2060036095 date "1991-01-01" @default.
- W2060036095 modified "2023-10-18" @default.
- W2060036095 title "Single chain antibody variable regions" @default.
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- W2060036095 doi "https://doi.org/10.1016/0167-7799(91)90044-i" @default.
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