FRINK Linked Data Fragments server

Matches in SemOpenAlex for { <https://semopenalex.org/work/W2060058297> ?p ?o ?g. }

• W2060058297 endingPage "34" @default.
• W2060058297 startingPage "28" @default.
• W2060058297 abstract "Herein, we combine the advantage of aptamer technique with the amplifying effect of an enzyme-free signal-amplification and Au nanoparticles (NPs) to design a sensitive surface plasmon resonance (SPR) aptasensor for detecting small molecules. This detection system consists of aptamer, detection probe (c-DNA1) partially hybridizing to the aptamer strand, Au NPs-linked hairpin DNA (Au-H-DNA1), and thiolated hairpin DNA (H-DNA2) previously immobilized on SPR gold chip. In the absence of target, the H-DNA1 possessing hairpin structure cannot hybridize with H-DNA2 and thereby Au NPs will not be captured on the SPR gold chip surface. Upon addition of target, the detection probe c-DNA1 is forced to dissociate from the c-DNA1/aptamer duplex by the specific recognition of the target to its aptamer. The released c-DNA1 hybridizes with Au-H-DNA1 and opens the hairpin structure, which accelerate the hybridization between Au-H-DNA1 and H-DNA2, leading to the displacement of the c-DNA1 through a branch migration process. The released c-DNA1 then hybridizes with another Au-H-DNA1 probe, and the cycle starts anew, resulting in the continuous immobilization of Au-H-DNA1 probes on the SPR chip, generating a significant change of SPR signal due to the electronic coupling interaction between the localized surface plasma of the Au NPs and the surface plasma wave. With the use of adenosine as a proof-of-principle analyte, this sensing platform can detect adenosine specifically with a detection limit as low as 0.21 pM, providing a simple, sensitive and selective protocol for small target molecules detection." @default.
• W2060058297 created "2016-06-24" @default.
• W2060058297 creator A5018916998 @default.
• W2060058297 creator A5019686308 @default.
• W2060058297 creator A5060474062 @default.
• W2060058297 creator A5066716873 @default.
• W2060058297 creator A5073101687 @default.
• W2060058297 date "2015-04-01" @default.
• W2060058297 modified "2023-09-30" @default.
• W2060058297 title "Enzyme-free surface plasmon resonance aptasensor for amplified detection of adenosine via target-triggering strand displacement cycle and Au nanoparticles" @default.
• W2060058297 cites W1964051406 @default.
• W2060058297 cites W1968905494 @default.
• W2060058297 cites W1969645755 @default.
• W2060058297 cites W1969912148 @default.
• W2060058297 cites W1973367885 @default.
• W2060058297 cites W1976568654 @default.
• W2060058297 cites W1977125458 @default.
• W2060058297 cites W1979469497 @default.
• W2060058297 cites W1981732861 @default.
• W2060058297 cites W1985468810 @default.
• W2060058297 cites W1986585549 @default.
• W2060058297 cites W1987395070 @default.
• W2060058297 cites W1988903031 @default.
• W2060058297 cites W2004760736 @default.
• W2060058297 cites W2007787260 @default.
• W2060058297 cites W2014435323 @default.
• W2060058297 cites W2015615857 @default.
• W2060058297 cites W2016384375 @default.
• W2060058297 cites W2017359768 @default.
• W2060058297 cites W2031942242 @default.
• W2060058297 cites W2045221143 @default.
• W2060058297 cites W2046212038 @default.
• W2060058297 cites W2048702576 @default.
• W2060058297 cites W2052032121 @default.
• W2060058297 cites W2056421966 @default.
• W2060058297 cites W2064030842 @default.
• W2060058297 cites W2069820826 @default.
• W2060058297 cites W2070389092 @default.
• W2060058297 cites W2071224672 @default.
• W2060058297 cites W2072938372 @default.
• W2060058297 cites W2077930830 @default.
• W2060058297 cites W2079732431 @default.
• W2060058297 cites W2080591407 @default.
• W2060058297 cites W2082112045 @default.
• W2060058297 cites W2083594284 @default.
• W2060058297 cites W2090262206 @default.
• W2060058297 cites W2094916010 @default.
• W2060058297 cites W2102699655 @default.
• W2060058297 cites W2115431938 @default.
• W2060058297 cites W2127159287 @default.
• W2060058297 cites W2129569338 @default.
• W2060058297 cites W2142995293 @default.
• W2060058297 cites W2161744546 @default.
• W2060058297 cites W2170347395 @default.
• W2060058297 cites W2318673848 @default.
• W2060058297 cites W2327881311 @default.
• W2060058297 cites W2330312460 @default.
• W2060058297 cites W2330920454 @default.
• W2060058297 cites W2331231542 @default.
• W2060058297 cites W2333363963 @default.
• W2060058297 doi "https://doi.org/10.1016/j.aca.2015.02.028" @default.
• W2060058297 hasPubMedId "https://pubmed.ncbi.nlm.nih.gov/25847158" @default.
• W2060058297 hasPublicationYear "2015" @default.
• W2060058297 type Work @default.
• W2060058297 sameAs 2060058297 @default.
• W2060058297 citedByCount "29" @default.
• W2060058297 countsByYear W20600582972015 @default.
• W2060058297 countsByYear W20600582972016 @default.
• W2060058297 countsByYear W20600582972017 @default.
• W2060058297 countsByYear W20600582972018 @default.
• W2060058297 countsByYear W20600582972019 @default.
• W2060058297 countsByYear W20600582972021 @default.
• W2060058297 countsByYear W20600582972022 @default.
• W2060058297 countsByYear W20600582972023 @default.
• W2060058297 crossrefType "journal-article" @default.
• W2060058297 hasAuthorship W2060058297A5018916998 @default.
• W2060058297 hasAuthorship W2060058297A5019686308 @default.
• W2060058297 hasAuthorship W2060058297A5060474062 @default.
• W2060058297 hasAuthorship W2060058297A5066716873 @default.
• W2060058297 hasAuthorship W2060058297A5073101687 @default.
• W2060058297 hasConcept C10390740 @default.
• W2060058297 hasConcept C106847996 @default.
• W2060058297 hasConcept C119128265 @default.
• W2060058297 hasConcept C128972844 @default.
• W2060058297 hasConcept C153911025 @default.
• W2060058297 hasConcept C155672457 @default.
• W2060058297 hasConcept C171250308 @default.
• W2060058297 hasConcept C185592680 @default.
• W2060058297 hasConcept C192562407 @default.
• W2060058297 hasConcept C21951064 @default.
• W2060058297 hasConcept C43617362 @default.
• W2060058297 hasConcept C86803240 @default.
• W2060058297 hasConceptScore W2060058297C10390740 @default.
• W2060058297 hasConceptScore W2060058297C106847996 @default.
• W2060058297 hasConceptScore W2060058297C119128265 @default.
• W2060058297 hasConceptScore W2060058297C128972844 @default.
• W2060058297 hasConceptScore W2060058297C153911025 @default.
• W2060058297 hasConceptScore W2060058297C155672457 @default.

• next