Matches in SemOpenAlex for { <https://semopenalex.org/work/W2060065983> ?p ?o ?g. }
Showing items 1 to 76 of
76
with 100 items per page.
- W2060065983 endingPage "96" @default.
- W2060065983 startingPage "93" @default.
- W2060065983 abstract "Various prostaglandins, particularly PGE2 and PGI2, appear to play a major role in osteolytic processes. The bone-destructive action of dental squamous cell cysts is thought to be caused or at least mediated by prostaglandins. Both leucotrienes and prostaglandins are synthesized from a common precursor substance, i.e. arachidonic acid, in a series of reactions. There is a special relation between leucotrienes and PGI2 in that PGI2 synthesis in endothelial cells can be enhanced by LTC4 and LTD4. R-TLC showed conversion of the arachidonic acid added into PGI2 in 8 out of 12 cases, as reflected by the stable degradation product 6-oxo-PGF1 alpha. In 8 cases bioassay showed PGI2 synthesis without addition of LTC4 and LTD4. Incremental LTC4 and LTD4 additions were found to cause a highly significant increase of PGI2 synthesis rates. In summary, LTC4 and LTD4 stimulate PGI2 synthesis in chronic inflammatory processes in vivo and may thus elicit or accelerate osteolysis." @default.
- W2060065983 created "2016-06-24" @default.
- W2060065983 creator A5031802447 @default.
- W2060065983 creator A5034445155 @default.
- W2060065983 creator A5060059706 @default.
- W2060065983 creator A5072719814 @default.
- W2060065983 creator A5078363086 @default.
- W2060065983 creator A5088253196 @default.
- W2060065983 date "1985-01-01" @default.
- W2060065983 modified "2023-10-13" @default.
- W2060065983 title "Evidence that PGI2-generationin human dental cysts is stimulated by leucotrienes C4 and D4" @default.
- W2060065983 cites W1979190457 @default.
- W2060065983 cites W1999399975 @default.
- W2060065983 cites W2021403302 @default.
- W2060065983 cites W2025819978 @default.
- W2060065983 cites W2045981686 @default.
- W2060065983 cites W2050252686 @default.
- W2060065983 cites W2086085664 @default.
- W2060065983 cites W2097781982 @default.
- W2060065983 cites W2132413543 @default.
- W2060065983 cites W2415058446 @default.
- W2060065983 cites W4245413917 @default.
- W2060065983 doi "https://doi.org/10.1016/s0301-0503(85)80023-0" @default.
- W2060065983 hasPubMedId "https://pubmed.ncbi.nlm.nih.gov/3889207" @default.
- W2060065983 hasPublicationYear "1985" @default.
- W2060065983 type Work @default.
- W2060065983 sameAs 2060065983 @default.
- W2060065983 citedByCount "10" @default.
- W2060065983 countsByYear W20600659832013 @default.
- W2060065983 countsByYear W20600659832022 @default.
- W2060065983 crossrefType "journal-article" @default.
- W2060065983 hasAuthorship W2060065983A5031802447 @default.
- W2060065983 hasAuthorship W2060065983A5034445155 @default.
- W2060065983 hasAuthorship W2060065983A5060059706 @default.
- W2060065983 hasAuthorship W2060065983A5072719814 @default.
- W2060065983 hasAuthorship W2060065983A5078363086 @default.
- W2060065983 hasAuthorship W2060065983A5088253196 @default.
- W2060065983 hasConcept C126322002 @default.
- W2060065983 hasConcept C181199279 @default.
- W2060065983 hasConcept C199343813 @default.
- W2060065983 hasConcept C2778078955 @default.
- W2060065983 hasConcept C2780664492 @default.
- W2060065983 hasConcept C2781282405 @default.
- W2060065983 hasConcept C55493867 @default.
- W2060065983 hasConcept C71924100 @default.
- W2060065983 hasConcept C86803240 @default.
- W2060065983 hasConceptScore W2060065983C126322002 @default.
- W2060065983 hasConceptScore W2060065983C181199279 @default.
- W2060065983 hasConceptScore W2060065983C199343813 @default.
- W2060065983 hasConceptScore W2060065983C2778078955 @default.
- W2060065983 hasConceptScore W2060065983C2780664492 @default.
- W2060065983 hasConceptScore W2060065983C2781282405 @default.
- W2060065983 hasConceptScore W2060065983C55493867 @default.
- W2060065983 hasConceptScore W2060065983C71924100 @default.
- W2060065983 hasConceptScore W2060065983C86803240 @default.
- W2060065983 hasLocation W20600659831 @default.
- W2060065983 hasLocation W20600659832 @default.
- W2060065983 hasOpenAccess W2060065983 @default.
- W2060065983 hasPrimaryLocation W20600659831 @default.
- W2060065983 hasRelatedWork W1994341761 @default.
- W2060065983 hasRelatedWork W1994910584 @default.
- W2060065983 hasRelatedWork W2016014768 @default.
- W2060065983 hasRelatedWork W2030807489 @default.
- W2060065983 hasRelatedWork W2039123883 @default.
- W2060065983 hasRelatedWork W2071089590 @default.
- W2060065983 hasRelatedWork W2074385407 @default.
- W2060065983 hasRelatedWork W2083118160 @default.
- W2060065983 hasRelatedWork W2336347171 @default.
- W2060065983 hasRelatedWork W327529633 @default.
- W2060065983 hasVolume "13" @default.
- W2060065983 isParatext "false" @default.
- W2060065983 isRetracted "false" @default.
- W2060065983 magId "2060065983" @default.
- W2060065983 workType "article" @default.