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• W2060083669 abstract "Lymphokine-activated killer cells generated from peripheral blood of Non-Hodgkin's lymphoma patients showed comparable levels of cytotoxicity. The patients with advanced disseminated disease displayed better augmentation with recombinant interleukin-2(rIL-2) than the patients with localized disease. Thus, the defective cytotoxic potential of patients could be corrected in a culture of effector cells with IL-2. The indigenous ability to produce IL-2 in response to activation of peripheral blood mononuclear cells with phytohemagglutin showed slight depression and a positive correlation with the stage of the disease. Phenotypic analysis revealed a heterogenous population of cells involved in cytotoxic activity. Thus, IL-2 merits further evaluation in malignant lymphomas, particularly in relation to other variable therapies in conjunction with chemotheraphy." @default.
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• W2060083669 date "1990-06-01" @default.
• W2060083669 modified "2023-10-16" @default.
• W2060083669 title "Generation and characterization of lymphokine-activated killer cells from non-Hodgkin's lymphoma patients" @default.
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• W2060083669 doi "https://doi.org/10.1016/0165-2478(90)90051-q" @default.
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