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- W206014796 abstract "The aminophospholipid translocase is a plasma membrane Mg2(+)-ATPase which selectively pumps the aminophospholipids (phosphatidylserine and phosphatidylethanolamine) from the outer to the inner monolayer in eukaryotic cells and is predominantly responsible for the asymmetric phospholipid distribution of the plasma membrane. Similar ATP-dependent transport of phospholipid takes place in some organelles such as chromaffin granules. On the other hand, the phospholipid flippase of rat liver endoplasmic reticulum does not require ATP and has a low lipid specificity. The biological implications of these phospholipid flippases are discussed." @default.
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- W206014796 date "1990-10-01" @default.
- W206014796 modified "2023-09-25" @default.
- W206014796 title "Control of the transmembrane phospholipid distribution in eukaryotic cells by aminophospholipid translocase." @default.
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