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- W2060156687 abstract "ABSTRACT Castrated young adult inbred male rats bearing ovarian transplants were subjected to electrical stimulation of the hypothalamus. This was done in order to investigate whether discharge of ovulatory amounts of gonadotrophins could be induced in such male animals by this procedure. Bilateral stimulations with unipolar electrodes and a DC current of 1.5 mA applied during 10 seconds induced in the ovarian grafts histological changes indicating the discharge of ovulatory amounts of gonadotrophins. In animals killed one day after stimulation these changes consisted of displacement of the ova towards the centre of the follicles with loosening of the cumulus oophorus. In one animal the ova had left the follicles. In animals killed three days after stimulation numerous young corpora lutea could be observed. These results were obtained with electrode tips either close to the median eminence, or in the preoptic area. Shamstimulations were ineffective. Some of the experimental animals received progesterone pretreatment. This rendered the stimulations ineffective, if continued until the day preceding stimulation, but seemed without effect on the results of stimulation, if two or three days without progesterone preceded the stimulations." @default.
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- W2060156687 date "1966-02-01" @default.
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- W2060156687 title "OVULATORY DISCHARGE OF GONADOTROPHINS INDUCED BY HYPOTHALAMIC STIMULATION IN CASTRATED MALE RATS BEARING A TRANSPLANTED OVARY" @default.
- W2060156687 doi "https://doi.org/10.1530/acta.0.0510281" @default.
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