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• W2060162022 abstract "An efficient diastereoselective oxa-Pictet-Spengler reaction strategy was developed to construct benzoisochroman diastereomers. The utility of the reaction was demonstrated in the context of both the total synthesis of naturally occurring pyranonaphthoquinones (+)-frenolicin B and epi-(+)-frenolicin B as well as a range of frenolicin precursor analogs. The method is versatile and offers exquisite stereocontrol and, as such, offers a synthetic advance for the synthesis of pyranonaphthoquinone analogs." @default.
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• W2060162022 date "2013-10-23" @default.
• W2060162022 modified "2023-09-24" @default.
• W2060162022 title "A Diastereoselective Oxa-Pictet–Spengler-Based Strategy for (+)-Frenolicin B and <i>epi</i>-(+)-Frenolicin B Synthesis" @default.
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• W2060162022 doi "https://doi.org/10.1021/ol4027649" @default.
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