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- W2060190889 abstract "Since the discovery of miRNAs, a number of miRNAs have been identified as p53's transcriptional targets. Most of them are involved in regulation of the known p53 functions, such as cell cycle, apoptosis and senescence. Our recent study revealed miR-1246 as a novel target of p53 and its analogs p63 and p73 to suppress the expression of DYRK1A and consequently activate NFAT, both of which are associated with Down syndrome and possibly with tumorigenesis. This finding suggests that miR-1246 might serve as a likely link of the p53 family with Down syndrome. Here, we provide some prospective views on the potential role of the p53 family in Down syndrome via miR-1246 and propose a new p53-miR-1246-DYRK1A-NFAT pathway in cancer." @default.
- W2060190889 created "2016-06-24" @default.
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- W2060190889 creator A5061151351 @default.
- W2060190889 creator A5066493327 @default.
- W2060190889 creator A5085788510 @default.
- W2060190889 date "2012-01-15" @default.
- W2060190889 modified "2023-09-29" @default.
- W2060190889 title "MiR-1246: A new link of the p53 family with cancer and Down syndrome" @default.
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- W2060190889 cites W1964567152 @default.
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- W2060190889 doi "https://doi.org/10.4161/cc.20809" @default.
- W2060190889 hasPubMedCentralId "https://www.ncbi.nlm.nih.gov/pmc/articles/3409007" @default.
- W2060190889 hasPubMedId "https://pubmed.ncbi.nlm.nih.gov/22751441" @default.
- W2060190889 hasPublicationYear "2012" @default.
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