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- W2060274864 abstract "Les maladies à cytomégalovirus (CMV) qui nécessitent un traitement antiviral spécifique surviennent majoritairement chez les patients immunodéprimés. Les modalités de ce traitement sont adaptées aux objectifs recherchés (traitements curatif et prophylactique) et tiennent compte de la nature de l'infection, de l'organe concerné et de l'origine de l'immunodépression sous-jacente. À ce jour, le nombre limité d'antiviraux spécifiques et l'émergence fréquente de souches virales résistantes, associés à l'accroissement des populations immunodéprimées confirment la nécessité de la mise à disposition d'une vaccination anti-CMv efficace. Although infections caused by cytomegalovirus (CMV) are common in normal host, CMV disease remains a major health threat in immunocompromised patients. Due to the clinical severity of these CMV diseases which is dependent on nature of infection and on the underlying immunosuppressive cause, antiviral chemotherapy modalities must be adapted to prevent and/or to treat these diseases. The limited number of active drugs and the increasing appearance of clinical resistance to these compound underline the impetus for research in the prevention of the far-reaching consequences of CMV infection and disease, and the urgently need of a CMV vaccination." @default.
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- W2060274864 date "2002-09-01" @default.
- W2060274864 modified "2023-09-23" @default.
- W2060274864 title "Chimiothérapie des infections à CMV et résistance aux antiviraux" @default.
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- W2060274864 doi "https://doi.org/10.1016/s0338-9898(02)80266-9" @default.
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