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• W2060297070 abstract "Describir las características de una seriede pacientes diagnosticados de enfermedad deVogt-Koyanagi-Harada (EVKH) seguidos en unaUnidad de Uveítis (multidisciplinaria, formada poroftalmólogos e internistas) en nuestro medio. Estudio retrospectivodescriptivo de 11 pacientes con EVKH (5 varonesy 6 mujeres; edad media al diagnóstico: 32,6 años) seguidos entre 1980 y 2003. Todos sufrieron panuveítis y/o desprendimiento exudativo de retina. Aparecieronalteraciones extraoculares en todos: neurológicasen el 63,7% (meningitis aséptica y/o síntomasfocales), dermatológicas en el 81,8% (vitíligo,canicie, poliosis, alopecia), hipoacusianeurosensorial (el 50% de pacientes conaudiometría) y síntomas generales en el 25%. Todos recibieron glucocorticoides sistémicos. Seañadió ciclosporina en 5 pacientes (45,4%) coninflamación de polo posterior y azatioprina en 2 por inflamación anterior. La agudeza visual finalfue > 0,5 en el 81,8% de los casos, pero 2 tuvieron mala evolución (uno, con catarata yqueratopatía en banda en ojo izquierdo y deteriorovisual grave, precisó vitrectomía derecha y en otrose desarrolló hipotensión ocular grave). Aparecieron complicaciones en otros 2 pacientes: catarata y glaucoma en uno y sinequias iridianassin glaucoma en otro. Encontramos menor frecuencia dedesprendimiento exudativo de retina y mayor dealteraciones dermatológicas que lo comunicado. Un porcentaje importante de casos precisóinmunosupresores. La agudeza visual final fuebuena en la mayoría de los pacientes. To describe the characteristics of a series of patients diagnosed of Vogt-Koyanagi-Harada disease (VKHD) and controlled by an Uveitis Unit (composed of ophthalmologists and internists) in our population. Retrospective descriptive study of 11 patients with VKHD (5 males and 6 women; median age at diagnosis 32.6 years old) followed-up between 1980 and 2003. All patients suffered panuveitis and/or exudative retinal detachment. Extraocular signs were present in all cases: neurological in 63.7% (aseptic meningitis and/or focal symptoms), cutaneous in 81.8% (vitiligo, whiteness, poliosis, alopecia), neurosensorial hypoacusis (50% of patients with audiometry), and general symptoms in 25%. They all received systemic corticosteroids. Cyclosporine was added in 5 patients (45.4%) with posterior uveitis, and azathioprine in 2 of them for iridocyclitis. The final visual acuity was 0.5 or better in 81.8% of cases, but 2 patients had an unfavourable evolution (one, who had cataract and band keratopathy in the left eye and severe visual worsening, needed right vitrectomy, and the other suffered severe ocular hypotension). Complications developed in 2 other patients: cataract and glaucoma in one, and synechiae without glaucoma in the other. We found less frequency of exudative retinal detachment and greater frequency of cutaneous signs than the communicated. A significant percentage of cases needed immunosuppressive agents. Final visual acuity was good in the majority of patients." @default.
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• W2060297070 date "2006-09-01" @default.
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• W2060297070 title "Enfermedad de Vogt-Koyanagi-Harada. Características de un grupo de pacientes andaluces" @default.
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• W2060297070 doi "https://doi.org/10.1157/13090507" @default.
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