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• W2060334493 abstract "The joint evolution of major and minor mutations influencing a quantitative character is modelled in a large population. Empirical data on natural and domesticated populations, and analysis of the models, suggests that strong selection sustained over several generations is usually required for adaptive evolution by a major mutation, in order to overcome deleterious pleiotropic effects generally associated with major mutations. This helps to explain why adaptive evolution by major mutations occurs much more frequently in domesticated and artificially disturbed populations than in natural ones." @default.
• W2060334493 created "2016-06-24" @default.
• W2060334493 creator A5049319800 @default.
• W2060334493 date "1983-02-01" @default.
• W2060334493 modified "2023-10-17" @default.
• W2060334493 title "The response to selection on major and minor mutations affecting a metrical trait" @default.
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• W2060334493 doi "https://doi.org/10.1038/hdy.1983.6" @default.
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