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- W2060349397 abstract "S U N D A Y 220 Does Monitoring of the Spirometric Values by Office Reflect Asthma Control After Discontinuing Controller Medication in Children with Controlled Asthma? Dong In Suh, MD, Ju Kyung Lee, Jun-Hyuk Song, Young Yull Y. Koh, MD, PhD; Seoul National University Hospital, Seoul, South Korea. RATIONALE: It is important to assess the level of control in asthmatic children who were well-controlled and thus discontinued controller medications. We have verified associations between lung function indices measured by a portable spirometer and clues for asthma exacerbation. METHODS: A total of 20 well-controlled children with persistent asthma were included. After discontinuing controller medications, each made follow-up visits at the 2nd, 6th, and 12th week. At each visit, spirometric values before and after bronchodilators were evaluated by a portable spirometer and clues for asthma exacerbation were assessed. We verified the association between the spirometric values i.e. forced expiratory volume in 1 second(FEV1), peak expiratory flow rate(PEFR), and indices of bronchodilator responses(BDRFEV1 and BDRPEFR) and clues for asthma exacerbation. RESULTS: Among20 children, 13(65%)were successfully followed-up for 12 weeks with asthma kept stable. Spirometric values including FEV1, PEFR, BDRFEV1 and BDRPEFR were not different not only among the time-points but also between thosewhowere stable and thosewho exhibited clues for asthma exacerbation. At every measurements, BDRFEV1 and BDRPEFR showed a good correlation(rp50.3807, p50.0011), but BDRPEFR tended to be higher than BDRFEV1 in those who presented clues for asthma exacerbation. CONCLUSIONS: When controller medications were discontinued in children with well-controlled asthma, many of them were able to maintain the stable condition. However, indicesmeasured by the portable spirometer failed to differentiate clues for asthma exacerbation. Office spirometry can be used only as an adjunctive tool to monitor the level of control in asthmatic children off the medication." @default.
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- W2060349397 date "2013-02-01" @default.
- W2060349397 modified "2023-09-27" @default.
- W2060349397 title "Does Monitoring of the Spirometric Values by Office Reflect Asthma Control After Discontinuing Controller Medication in Children with Controlled Asthma?" @default.
- W2060349397 doi "https://doi.org/10.1016/j.jaci.2012.12.882" @default.
- W2060349397 hasPublicationYear "2013" @default.
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