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• W2060369084 abstract "Aims & Methods: We carried out a multicenter prospective study of the complication incidences, and particularly the factors involving pancreatitis in ERCP-related procedures. An uncontrolled prospective study was conducted of complications of ERCP for all patients undergoing the procedure at thirteen hospitals in Hokkaido, Japan. The enrollment period was between October 2003 and August 2004. All patients who underwent ERCP were eligible for inclusion; the exclusion criteria were inability to perform ERCP because of an obstructed duodenum and performed endoscopic papillectomy. Before ERCP procedure, we confirm function of the accessory papilla by dye sprinkling method. A complication of ERCP was defined and graded into categories of severity as proposed by Cotton et al. We examined in this study i)success rates of the procedures, ii)incidences of complications and their categories of severity, and iii) factors involving post-ERCP pancreatitis (sex, age, function of accessory papilla, previous history of pancreatitis, time required for the techniques, underwent imaging of pancreatic duct with contrast medium). Results: i) Of the 2306 cases, the procedures were for diagnostic ERCP in 751 and for therapeutic ERCP in 1555. The overall success rate was 96.6%(2228/2306). ii) The overall complication incidence was 5.03%(116 cases) in the diagnostic ERCP, 4.39%, and in the therapeutic ERCP, 5.34%. Pancreatitis was occurred in 69 cases (severe in 10, moderate in 24, mild in 35), hemorrhage in 8 (1, 3, 4), perforation in 4 (1, 3, 0), cholangitis and cholecystitis in 21 (0, 13, 8). The procedure related mortality was one case (0.043%) which was severe post-EST pancreatitis. iii) Incidences of post-ERCP pancreatitis were as follows: No history of trans-papillary treatment, 61/1461 (4.175) and has history of trans-papillary treatment, 8/845 (0.947) (p < 0.001). For those with good accessory papilla function, 9/402(2.239) , and those with poor function, 31/535 (5.794) (p = 0.0124). ;For the cases which required 30 minutes or over, 41/929 (4.413), and those less than 30 minutes, 28/1355(2.066) (p = 0.002). For those who underwent imaging of pancreatic duct with contrast medium, 54/1283 (4.209), and those who did not, 15/1023 (1.466) (p = 0.0002). Conclusion: The incidence of ERCP-related complications was 5.44% and ERCP-related mortality was 0.043%. The post-ERCP pancreatitis incidence was significantly high in patients with no history of trans-papillary treatment, poor function of accesary papilla, unsuccessful procedure, procedure time (over 30 min), difficult cannulation, visualization of pancreatic duct." @default.
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• W2060369084 date "2006-04-01" @default.
• W2060369084 modified "2023-09-27" @default.
• W2060369084 title "Complications of ERCP - A Multicenter Prospective Study" @default.
• W2060369084 doi "https://doi.org/10.1016/j.gie.2006.03.786" @default.
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