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- W2060391384 startingPage "248" @default.
- W2060391384 abstract "Peripheral T-cell lymphoma (PTCL) is a rare and heterogeneous group of non-Hodgkin lymphomas (NHLs). Whereas the incidence of the disease appears to increase during last decades and the prognosis remains dramatically poor, so far no standard treatment has been established. High-dose chemotherapy and autologous stem cell transplantation (HDT–ASCT) has been proven effective in relapsed PTCL, while retrospective studies have shown a survival benefit as first-line treatment in some subsets of PTCL patients. However, given disease rarity, there is a paucity of randomized trials in both upfront and relapse setting. Here, we critically evaluated eligible prospective and retrospective studies that address the role of ASCT in treatment of PTCL, with respect to quality of design and performance. Additionally, the role of allogeneic transplantation has been reviewed. The comparison of ASCT with novel agents that emerge or the combination of both, are to be ascertained via prospective randomized trials in this field." @default.
- W2060391384 created "2016-06-24" @default.
- W2060391384 creator A5044318093 @default.
- W2060391384 creator A5056643910 @default.
- W2060391384 date "2014-02-01" @default.
- W2060391384 modified "2023-10-14" @default.
- W2060391384 title "Peripheral T-cell lymphoma: The role of hematopoietic stem cell transplantation" @default.
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- W2060391384 doi "https://doi.org/10.1016/j.critrevonc.2013.08.016" @default.
- W2060391384 hasPubMedId "https://pubmed.ncbi.nlm.nih.gov/24075060" @default.
- W2060391384 hasPublicationYear "2014" @default.
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