Matches in SemOpenAlex for { <https://semopenalex.org/work/W2060418285> ?p ?o ?g. }
Showing items 1 to 92 of
92
with 100 items per page.
- W2060418285 endingPage "888" @default.
- W2060418285 startingPage "885" @default.
- W2060418285 abstract "An in vitro bioassay for plasma PRL-releasing factor-like activity has been developed. The method is a three-phase methanol extraction of plasma with extracts of 1.0 ml plasma adjusted to a final volume of 50 microliter. Single 50-microliter aliquots of extract were incubated in 1.0 ml Krebs-Ringer phosphate (KRP) buffer with one rat hemipituitary after a 1-h preincubation. Samples were obtained basally and 30 min after addition of the extract. During each set of incubations, a parallel series of hemipituitaries was incubated in KRP alone. The total nanograms of rat PRL released per mg pituitary tissue during the initial 30 min after preincubation was calculated for all studies. The mean quantity released in KRP alone was considered basal and was subtracted from values obtained during incubation with plasma extracts. The quantity remaining was considered PRL-releasing activity (PRA) of plasma, expressed as nanograms of rat PRL released per mg pituitary. The PRA in plasma from 13 patients with the amenorrhea-galactorrhea syndrome was 132 +/- 17 ng/mg pituitary (X +/- SE), which was significantly greater (P less than 0.001) than the PRA in plasma from eight matched controls [31 +/- 10 ng/mg pituitary (X +/- SE)]. The patients' individual PRL levels were elevated (range, 48-248 ng/ml), and when compared to the PRA in the samples, a highly significant (P less than 0.001) positive correlation evolved. These results indicate that a circulating PRL-releasing factor-like material present in normal plasma is higher in plasma from hyperprolactinemic patients in direct relationship to the PRL concentration. It is possible that this material is related to the pathogenesis of PRL-secreting pituitary disorders." @default.
- W2060418285 created "2016-06-24" @default.
- W2060418285 creator A5021418693 @default.
- W2060418285 creator A5025690610 @default.
- W2060418285 date "1978-10-01" @default.
- W2060418285 modified "2023-09-25" @default.
- W2060418285 title "Plasma Prolactin-Releasing Factor-Like Activity in the Amenorrhea-Galactorrhea Syndrome*" @default.
- W2060418285 cites W1530509338 @default.
- W2060418285 cites W1975636860 @default.
- W2060418285 cites W1987394161 @default.
- W2060418285 cites W2001331782 @default.
- W2060418285 cites W2003649322 @default.
- W2060418285 cites W2009044591 @default.
- W2060418285 cites W2009646672 @default.
- W2060418285 cites W2013534484 @default.
- W2060418285 cites W2015703184 @default.
- W2060418285 cites W2017638447 @default.
- W2060418285 cites W2034407150 @default.
- W2060418285 cites W2047524766 @default.
- W2060418285 cites W2053914776 @default.
- W2060418285 cites W2064696831 @default.
- W2060418285 cites W2072096359 @default.
- W2060418285 cites W2085219770 @default.
- W2060418285 cites W2106479921 @default.
- W2060418285 cites W2155520723 @default.
- W2060418285 cites W2312586582 @default.
- W2060418285 cites W2340732143 @default.
- W2060418285 doi "https://doi.org/10.1210/jcem-47-4-885" @default.
- W2060418285 hasPubMedId "https://pubmed.ncbi.nlm.nih.gov/122415" @default.
- W2060418285 hasPublicationYear "1978" @default.
- W2060418285 type Work @default.
- W2060418285 sameAs 2060418285 @default.
- W2060418285 citedByCount "14" @default.
- W2060418285 crossrefType "journal-article" @default.
- W2060418285 hasAuthorship W2060418285A5021418693 @default.
- W2060418285 hasAuthorship W2060418285A5025690610 @default.
- W2060418285 hasConcept C126322002 @default.
- W2060418285 hasConcept C134018914 @default.
- W2060418285 hasConcept C176685330 @default.
- W2060418285 hasConcept C185592680 @default.
- W2060418285 hasConcept C25642318 @default.
- W2060418285 hasConcept C2777658017 @default.
- W2060418285 hasConcept C2777863693 @default.
- W2060418285 hasConcept C2778024521 @default.
- W2060418285 hasConcept C2778058571 @default.
- W2060418285 hasConcept C2779064019 @default.
- W2060418285 hasConcept C2779234561 @default.
- W2060418285 hasConcept C2779306644 @default.
- W2060418285 hasConcept C54355233 @default.
- W2060418285 hasConcept C55493867 @default.
- W2060418285 hasConcept C71315377 @default.
- W2060418285 hasConcept C71924100 @default.
- W2060418285 hasConcept C86803240 @default.
- W2060418285 hasConceptScore W2060418285C126322002 @default.
- W2060418285 hasConceptScore W2060418285C134018914 @default.
- W2060418285 hasConceptScore W2060418285C176685330 @default.
- W2060418285 hasConceptScore W2060418285C185592680 @default.
- W2060418285 hasConceptScore W2060418285C25642318 @default.
- W2060418285 hasConceptScore W2060418285C2777658017 @default.
- W2060418285 hasConceptScore W2060418285C2777863693 @default.
- W2060418285 hasConceptScore W2060418285C2778024521 @default.
- W2060418285 hasConceptScore W2060418285C2778058571 @default.
- W2060418285 hasConceptScore W2060418285C2779064019 @default.
- W2060418285 hasConceptScore W2060418285C2779234561 @default.
- W2060418285 hasConceptScore W2060418285C2779306644 @default.
- W2060418285 hasConceptScore W2060418285C54355233 @default.
- W2060418285 hasConceptScore W2060418285C55493867 @default.
- W2060418285 hasConceptScore W2060418285C71315377 @default.
- W2060418285 hasConceptScore W2060418285C71924100 @default.
- W2060418285 hasConceptScore W2060418285C86803240 @default.
- W2060418285 hasIssue "4" @default.
- W2060418285 hasLocation W20604182851 @default.
- W2060418285 hasLocation W20604182852 @default.
- W2060418285 hasOpenAccess W2060418285 @default.
- W2060418285 hasPrimaryLocation W20604182851 @default.
- W2060418285 hasRelatedWork W1990896009 @default.
- W2060418285 hasRelatedWork W1999551355 @default.
- W2060418285 hasRelatedWork W2029486896 @default.
- W2060418285 hasRelatedWork W2033209790 @default.
- W2060418285 hasRelatedWork W2080367469 @default.
- W2060418285 hasRelatedWork W2086925194 @default.
- W2060418285 hasRelatedWork W2152306407 @default.
- W2060418285 hasRelatedWork W2153052119 @default.
- W2060418285 hasRelatedWork W2161296685 @default.
- W2060418285 hasRelatedWork W1974735784 @default.
- W2060418285 hasVolume "47" @default.
- W2060418285 isParatext "false" @default.
- W2060418285 isRetracted "false" @default.
- W2060418285 magId "2060418285" @default.
- W2060418285 workType "article" @default.