Matches in SemOpenAlex for { <https://semopenalex.org/work/W2060434516> ?p ?o ?g. }
Showing items 1 to 79 of
79
with 100 items per page.
- W2060434516 abstract "Rationale Whilst providing oxygen supplementation for an oxygen saturation (SpO 2 ) 2 ≥90% has not been demonstrated. With no evidence base, UK bronchiolitis guidelines (SIGN 91) recommend maintaining SpO 2 ≥ 94%, whilst US guidelines recommend ≥90%. This study tests the effect of supplementing oxygen to a limit of 90% SpO 2 on recovery in infants with acute viral bronchiolitis. Methods We performed a double-blind randomised controlled equivalence study in 8 paediatric hospitals in the UK over two winter 6-month seasons (2011/12, 2012/13). Infants >6 weeks and ≤12 months corrected age were eligible to be randomised if they were diagnosed with bronchiolitis by an emergency department clinician and were to be admitted to hospital. Infants were randomised to either a standard pulse oximeter or a modified pulse oximeter (Rad-8, Masimo, CA). Modified oximeters would display SpO 2 94 when actual SpO 2 was 90% (smoothed readings above and below). Infants were followed up by standardised telephone calls at 7, 14, 28 days and 6 months. Results 615 infants were randomised. 352 males, 263 female, Mean age 4.9 months (iqr 2.7–7.3). The effect of oxygen supplementation on recovery was measured by time to resolution of cough (primary outcome), time back to normal (parent perception), recovery of heart rate and respiratory rate, and need for oxygen supplementation during admission, number of healthcare re-attendances post discharge. The study database is now locked and a full analysis will be presented. Conclusion In infants admitted to hospital with acute bronchiolitis, the effect of a target oxygen saturation of 90% on symptom recovery and healthcare re-attendance will be discussed. The results may help inform discussion on use of oxygen for symptom resolution and future healthcare planning, including the current use of home delivery of supplemental oxygen in acute viral bronchiolitis. Funded by UK NIHR HTA (http://www.nets.nihr.ac.uk/projects/hta/099116). Oximetry kindly supportedby Masimo Corporation Ltd." @default.
- W2060434516 created "2016-06-24" @default.
- W2060434516 creator A5010172983 @default.
- W2060434516 creator A5056023987 @default.
- W2060434516 creator A5068236105 @default.
- W2060434516 date "2014-04-01" @default.
- W2060434516 modified "2023-09-24" @default.
- W2060434516 title "G90 Effect Of Accepting Lower Oxygen Saturation Target (90%) On Recovery From Acute Viral Bronchiolitis (BIDS trial): A Multi-Centre Double-Blind Randomised Equivalence Trial" @default.
- W2060434516 doi "https://doi.org/10.1136/archdischild-2014-306237.90" @default.
- W2060434516 hasPublicationYear "2014" @default.
- W2060434516 type Work @default.
- W2060434516 sameAs 2060434516 @default.
- W2060434516 citedByCount "1" @default.
- W2060434516 countsByYear W20604345162015 @default.
- W2060434516 crossrefType "journal-article" @default.
- W2060434516 hasAuthorship W2060434516A5010172983 @default.
- W2060434516 hasAuthorship W2060434516A5056023987 @default.
- W2060434516 hasAuthorship W2060434516A5068236105 @default.
- W2060434516 hasConcept C126322002 @default.
- W2060434516 hasConcept C168563851 @default.
- W2060434516 hasConcept C178790620 @default.
- W2060434516 hasConcept C185592680 @default.
- W2060434516 hasConcept C187212893 @default.
- W2060434516 hasConcept C194828623 @default.
- W2060434516 hasConcept C2777953023 @default.
- W2060434516 hasConcept C2778821649 @default.
- W2060434516 hasConcept C2780124106 @default.
- W2060434516 hasConcept C2909094123 @default.
- W2060434516 hasConcept C42219234 @default.
- W2060434516 hasConcept C534529494 @default.
- W2060434516 hasConcept C540031477 @default.
- W2060434516 hasConcept C71924100 @default.
- W2060434516 hasConcept C76538665 @default.
- W2060434516 hasConcept C8213797 @default.
- W2060434516 hasConcept C84393581 @default.
- W2060434516 hasConceptScore W2060434516C126322002 @default.
- W2060434516 hasConceptScore W2060434516C168563851 @default.
- W2060434516 hasConceptScore W2060434516C178790620 @default.
- W2060434516 hasConceptScore W2060434516C185592680 @default.
- W2060434516 hasConceptScore W2060434516C187212893 @default.
- W2060434516 hasConceptScore W2060434516C194828623 @default.
- W2060434516 hasConceptScore W2060434516C2777953023 @default.
- W2060434516 hasConceptScore W2060434516C2778821649 @default.
- W2060434516 hasConceptScore W2060434516C2780124106 @default.
- W2060434516 hasConceptScore W2060434516C2909094123 @default.
- W2060434516 hasConceptScore W2060434516C42219234 @default.
- W2060434516 hasConceptScore W2060434516C534529494 @default.
- W2060434516 hasConceptScore W2060434516C540031477 @default.
- W2060434516 hasConceptScore W2060434516C71924100 @default.
- W2060434516 hasConceptScore W2060434516C76538665 @default.
- W2060434516 hasConceptScore W2060434516C8213797 @default.
- W2060434516 hasConceptScore W2060434516C84393581 @default.
- W2060434516 hasLocation W20604345161 @default.
- W2060434516 hasOpenAccess W2060434516 @default.
- W2060434516 hasPrimaryLocation W20604345161 @default.
- W2060434516 hasRelatedWork W1760694140 @default.
- W2060434516 hasRelatedWork W1941858017 @default.
- W2060434516 hasRelatedWork W1978322489 @default.
- W2060434516 hasRelatedWork W2045761706 @default.
- W2060434516 hasRelatedWork W2119338172 @default.
- W2060434516 hasRelatedWork W2133821509 @default.
- W2060434516 hasRelatedWork W2138691565 @default.
- W2060434516 hasRelatedWork W2143208626 @default.
- W2060434516 hasRelatedWork W2143348774 @default.
- W2060434516 hasRelatedWork W2159774234 @default.
- W2060434516 hasRelatedWork W2162742958 @default.
- W2060434516 hasRelatedWork W2222246409 @default.
- W2060434516 hasRelatedWork W2509190120 @default.
- W2060434516 hasRelatedWork W2560618459 @default.
- W2060434516 hasRelatedWork W2583256439 @default.
- W2060434516 hasRelatedWork W2751922513 @default.
- W2060434516 hasRelatedWork W2770932642 @default.
- W2060434516 hasRelatedWork W2806680508 @default.
- W2060434516 hasRelatedWork W3016638588 @default.
- W2060434516 hasRelatedWork W3134071112 @default.
- W2060434516 isParatext "false" @default.
- W2060434516 isRetracted "false" @default.
- W2060434516 magId "2060434516" @default.
- W2060434516 workType "article" @default.