Matches in SemOpenAlex for { <https://semopenalex.org/work/W2060478433> ?p ?o ?g. }
- W2060478433 endingPage "1410" @default.
- W2060478433 startingPage "1403" @default.
- W2060478433 abstract "<b>Background:</b> Leukoaraiosis (LA) is closely associated with aging, a major determinant of clinical outcome after ischemic stroke. In this study we sought to identify whether LA, independent of advancing age, affects outcome after acute ischemic stroke. <b>Methods:</b> LA volume was quantified in 240 patients with ischemic stroke and MRI within 24 hours of symptom onset. We explored the relationship between LA volume at admission and clinical outcome at 6 months, as assessed by the modified Rankin Scale (mRS). An ordinal logistic regression model was developed to analyze the independent effect of LA volume on clinical outcome. <b>Results:</b> Bivariate analyses showed a significant correlation between LA volume and mRS at 6 months (<i>r</i> = 0.19, <i>p</i> = 0.003). Mean mRS was 1.7 ± 1.8 among those in the lowest (≤1.2 mL) and 2.5 ± 1.9 in the highest (>9.9 mL) quartiles of LA volume (<i>p</i> = 0.01). The unfavorable prognostic effect of LA volume on clinical outcome was retained in the multivariable model (<i>p</i> = 0.002), which included age, gender, stroke risk factors (hypertension, diabetes mellitus, atrial fibrillation), previous history of brain infarction, admission plasma glucose level, admission NIH Stroke Scale score, IV rtPA treatment, and acute infarct volume on MRI as covariates. <b>Conclusions:</b> The volume of leukoaraiosis is a predictor of clinical outcome after ischemic stroke and this relationship persists after adjustment for important prognostic factors including age, initial stroke severity, and infarct volume." @default.
- W2060478433 created "2016-06-24" @default.
- W2060478433 creator A5000644127 @default.
- W2060478433 creator A5004980235 @default.
- W2060478433 creator A5004999727 @default.
- W2060478433 creator A5006664647 @default.
- W2060478433 creator A5015783013 @default.
- W2060478433 creator A5030528983 @default.
- W2060478433 creator A5031248234 @default.
- W2060478433 creator A5038428624 @default.
- W2060478433 creator A5061020099 @default.
- W2060478433 creator A5068460102 @default.
- W2060478433 creator A5079863121 @default.
- W2060478433 creator A5083669835 @default.
- W2060478433 date "2009-04-20" @default.
- W2060478433 modified "2023-10-16" @default.
- W2060478433 title "Severity of leukoaraiosis correlates with clinical outcome after ischemic stroke" @default.
- W2060478433 cites W1843498179 @default.
- W2060478433 cites W1912527095 @default.
- W2060478433 cites W1970041354 @default.
- W2060478433 cites W1972257422 @default.
- W2060478433 cites W1975191968 @default.
- W2060478433 cites W1979346069 @default.
- W2060478433 cites W1987806888 @default.
- W2060478433 cites W2000291174 @default.
- W2060478433 cites W2007952066 @default.
- W2060478433 cites W2012730616 @default.
- W2060478433 cites W2023540892 @default.
- W2060478433 cites W2026921532 @default.
- W2060478433 cites W2030472502 @default.
- W2060478433 cites W2035572126 @default.
- W2060478433 cites W2038145343 @default.
- W2060478433 cites W2049777870 @default.
- W2060478433 cites W2056592534 @default.
- W2060478433 cites W2063122692 @default.
- W2060478433 cites W2069338678 @default.
- W2060478433 cites W2072565932 @default.
- W2060478433 cites W2075389323 @default.
- W2060478433 cites W2078377297 @default.
- W2060478433 cites W2082973699 @default.
- W2060478433 cites W2084948736 @default.
- W2060478433 cites W2094219604 @default.
- W2060478433 cites W2100078230 @default.
- W2060478433 cites W2101163891 @default.
- W2060478433 cites W2104736983 @default.
- W2060478433 cites W2107707946 @default.
- W2060478433 cites W2113050969 @default.
- W2060478433 cites W2116506765 @default.
- W2060478433 cites W2117359502 @default.
- W2060478433 cites W2129257169 @default.
- W2060478433 cites W2131943911 @default.
- W2060478433 cites W2138166458 @default.
- W2060478433 cites W2142914335 @default.
- W2060478433 cites W2152488179 @default.
- W2060478433 cites W2292308933 @default.
- W2060478433 cites W2334509873 @default.
- W2060478433 doi "https://doi.org/10.1212/wnl.0b013e3181a18823" @default.
- W2060478433 hasPubMedCentralId "https://www.ncbi.nlm.nih.gov/pmc/articles/2677507" @default.
- W2060478433 hasPubMedId "https://pubmed.ncbi.nlm.nih.gov/19380699" @default.
- W2060478433 hasPublicationYear "2009" @default.
- W2060478433 type Work @default.
- W2060478433 sameAs 2060478433 @default.
- W2060478433 citedByCount "187" @default.
- W2060478433 countsByYear W20604784332012 @default.
- W2060478433 countsByYear W20604784332013 @default.
- W2060478433 countsByYear W20604784332014 @default.
- W2060478433 countsByYear W20604784332015 @default.
- W2060478433 countsByYear W20604784332016 @default.
- W2060478433 countsByYear W20604784332017 @default.
- W2060478433 countsByYear W20604784332018 @default.
- W2060478433 countsByYear W20604784332019 @default.
- W2060478433 countsByYear W20604784332020 @default.
- W2060478433 countsByYear W20604784332021 @default.
- W2060478433 countsByYear W20604784332022 @default.
- W2060478433 countsByYear W20604784332023 @default.
- W2060478433 crossrefType "journal-article" @default.
- W2060478433 hasAuthorship W2060478433A5000644127 @default.
- W2060478433 hasAuthorship W2060478433A5004980235 @default.
- W2060478433 hasAuthorship W2060478433A5004999727 @default.
- W2060478433 hasAuthorship W2060478433A5006664647 @default.
- W2060478433 hasAuthorship W2060478433A5015783013 @default.
- W2060478433 hasAuthorship W2060478433A5030528983 @default.
- W2060478433 hasAuthorship W2060478433A5031248234 @default.
- W2060478433 hasAuthorship W2060478433A5038428624 @default.
- W2060478433 hasAuthorship W2060478433A5061020099 @default.
- W2060478433 hasAuthorship W2060478433A5068460102 @default.
- W2060478433 hasAuthorship W2060478433A5079863121 @default.
- W2060478433 hasAuthorship W2060478433A5083669835 @default.
- W2060478433 hasBestOaLocation W20604784332 @default.
- W2060478433 hasConcept C126322002 @default.
- W2060478433 hasConcept C127413603 @default.
- W2060478433 hasConcept C134018914 @default.
- W2060478433 hasConcept C151956035 @default.
- W2060478433 hasConcept C164705383 @default.
- W2060478433 hasConcept C2776191500 @default.
- W2060478433 hasConcept C2777798775 @default.
- W2060478433 hasConcept C2779134260 @default.
- W2060478433 hasConcept C2779161974 @default.