Matches in SemOpenAlex for { <https://semopenalex.org/work/W2060483090> ?p ?o ?g. }
Showing items 1 to 97 of
97
with 100 items per page.
- W2060483090 abstract "The present studies have investigated the use of primed cytotoxic T cells (CTL) for the purpose of detecting the presence of an MHC disparate allogeneic cell population. The findings indicate that restimulation of primed CTL in the presence of activated T cell supernatants is an extremely sensitive method capable of detecting one allogeneic cell within a population containing 10,000 total cells (0.01%). In addition, this primed lymphocyte cytotoxicity assay (PLCA) was shown to be at least as accurate as flow cytometric analysis in determination of low numbers and percentages of allogeneic cells within the cell population being examined. Furthermore, the nature of the allogeneic mononuclear population did not influence the sensitivity or accuracy of this method. To examine this method's applicability for the detection of chimeric populations in vivo, spleen and thymic tissue from neonatally tolerized animals were examined by PLCA analysis. Allogeneic cells were readily detected in 100% of individual host spleen and thymuses tested. In total, the results showed that the PLCA is a highly reproducible and accurate method for the detection of extremely low numbers of allogeneic cells. This approach should be useful to monitor the presence of foreign cells in experimental and clinical situations in which individuals are exposed to allogeneic cell populations." @default.
- W2060483090 created "2016-06-24" @default.
- W2060483090 creator A5084690615 @default.
- W2060483090 creator A5091091106 @default.
- W2060483090 date "1990-02-01" @default.
- W2060483090 modified "2023-09-26" @default.
- W2060483090 title "The use of primed cytotoxic T lymphocytes as a highly sensitive and accurate method for the detection of MHC disparate allogeneic cells" @default.
- W2060483090 cites W1510356846 @default.
- W2060483090 cites W1522396705 @default.
- W2060483090 cites W1523014057 @default.
- W2060483090 cites W1534413127 @default.
- W2060483090 cites W1555915074 @default.
- W2060483090 cites W1606727434 @default.
- W2060483090 cites W1646154561 @default.
- W2060483090 cites W1729035541 @default.
- W2060483090 cites W1966697776 @default.
- W2060483090 cites W1967702267 @default.
- W2060483090 cites W1975029709 @default.
- W2060483090 cites W1999626234 @default.
- W2060483090 cites W2005905661 @default.
- W2060483090 cites W2035387224 @default.
- W2060483090 cites W2041592087 @default.
- W2060483090 cites W2047789932 @default.
- W2060483090 cites W2048698038 @default.
- W2060483090 cites W2058746374 @default.
- W2060483090 cites W2059493833 @default.
- W2060483090 cites W2081115308 @default.
- W2060483090 cites W2084093106 @default.
- W2060483090 cites W2091996781 @default.
- W2060483090 cites W2120370266 @default.
- W2060483090 cites W2131260695 @default.
- W2060483090 cites W2132636355 @default.
- W2060483090 cites W2415854561 @default.
- W2060483090 cites W1557801363 @default.
- W2060483090 doi "https://doi.org/10.1016/0022-1759(90)90343-t" @default.
- W2060483090 hasPubMedId "https://pubmed.ncbi.nlm.nih.gov/2319143" @default.
- W2060483090 hasPublicationYear "1990" @default.
- W2060483090 type Work @default.
- W2060483090 sameAs 2060483090 @default.
- W2060483090 citedByCount "0" @default.
- W2060483090 crossrefType "journal-article" @default.
- W2060483090 hasAuthorship W2060483090A5084690615 @default.
- W2060483090 hasAuthorship W2060483090A5091091106 @default.
- W2060483090 hasConcept C109316439 @default.
- W2060483090 hasConcept C137061746 @default.
- W2060483090 hasConcept C147483822 @default.
- W2060483090 hasConcept C147969180 @default.
- W2060483090 hasConcept C1491633281 @default.
- W2060483090 hasConcept C153911025 @default.
- W2060483090 hasConcept C154317977 @default.
- W2060483090 hasConcept C167672396 @default.
- W2060483090 hasConcept C202751555 @default.
- W2060483090 hasConcept C203014093 @default.
- W2060483090 hasConcept C207936829 @default.
- W2060483090 hasConcept C2780931953 @default.
- W2060483090 hasConcept C2908647359 @default.
- W2060483090 hasConcept C54355233 @default.
- W2060483090 hasConcept C553184892 @default.
- W2060483090 hasConcept C71924100 @default.
- W2060483090 hasConcept C86803240 @default.
- W2060483090 hasConcept C99454951 @default.
- W2060483090 hasConceptScore W2060483090C109316439 @default.
- W2060483090 hasConceptScore W2060483090C137061746 @default.
- W2060483090 hasConceptScore W2060483090C147483822 @default.
- W2060483090 hasConceptScore W2060483090C147969180 @default.
- W2060483090 hasConceptScore W2060483090C1491633281 @default.
- W2060483090 hasConceptScore W2060483090C153911025 @default.
- W2060483090 hasConceptScore W2060483090C154317977 @default.
- W2060483090 hasConceptScore W2060483090C167672396 @default.
- W2060483090 hasConceptScore W2060483090C202751555 @default.
- W2060483090 hasConceptScore W2060483090C203014093 @default.
- W2060483090 hasConceptScore W2060483090C207936829 @default.
- W2060483090 hasConceptScore W2060483090C2780931953 @default.
- W2060483090 hasConceptScore W2060483090C2908647359 @default.
- W2060483090 hasConceptScore W2060483090C54355233 @default.
- W2060483090 hasConceptScore W2060483090C553184892 @default.
- W2060483090 hasConceptScore W2060483090C71924100 @default.
- W2060483090 hasConceptScore W2060483090C86803240 @default.
- W2060483090 hasConceptScore W2060483090C99454951 @default.
- W2060483090 hasLocation W20604830901 @default.
- W2060483090 hasLocation W20604830902 @default.
- W2060483090 hasOpenAccess W2060483090 @default.
- W2060483090 hasPrimaryLocation W20604830901 @default.
- W2060483090 hasRelatedWork W1525937711 @default.
- W2060483090 hasRelatedWork W1553011016 @default.
- W2060483090 hasRelatedWork W1964986315 @default.
- W2060483090 hasRelatedWork W1993875521 @default.
- W2060483090 hasRelatedWork W1995789187 @default.
- W2060483090 hasRelatedWork W2041811834 @default.
- W2060483090 hasRelatedWork W2053177727 @default.
- W2060483090 hasRelatedWork W2076924768 @default.
- W2060483090 hasRelatedWork W2079283867 @default.
- W2060483090 hasRelatedWork W4290205309 @default.
- W2060483090 isParatext "false" @default.
- W2060483090 isRetracted "false" @default.
- W2060483090 magId "2060483090" @default.
- W2060483090 workType "article" @default.