FRINK Linked Data Fragments server

Matches in SemOpenAlex for { <https://semopenalex.org/work/W2060494829> ?p ?o ?g. }

• W2060494829 endingPage "118" @default.
• W2060494829 startingPage "112" @default.
• W2060494829 abstract "To investigate the factors affecting endothelial-cell retraction, we have studied the interaction of tumor cells with endothelial cells in 2 human pancreatic cancer cell lines, PSN-1 and MiaPaca-2. The extent of endothelial-cell retraction measured by the amount of intercellular junctional transport of F1TC-dextran through an endothelial monolayer was increased by the addition of a conditioned medium (CM) from both cell lines, while CM from PSN-I cells was 2 to 3 times more potent than that from MiaPaca-2 cells. After the treatment of endothelial monolayer with CM of PSN-1 cells, the ability of both PSN-1 cells and MiaPaca cells to adhere to or invade the monolayer increased. The addition of CM from PSN-1 cells did not affect the growth rate of either the endothelial or the tumor cells. The activity in the CM was heat-stable and bound to heparin-Sepharose, but was inactivated when treated by 0.5% trypsin. Protease inhibitors did not influence the activity. Pre-treatment of PSN-I cells by an inhibitor of protein synthesis, cyclohexi-mide, or of protein processing, benzyl-N-acetyl-a-D-galactos-aminide, reduced endothelial-cell-retraction activity in the CM. The active substance in the CM fractionated in the molecular-weight range of 10,000 to 50,000. These results suggest that PSN-1 cells produce and secrete (a) soluble factor(s) that can induce endothelial-cell retraction, thus facilitating tumor-cell invasion." @default.
• W2060494829 created "2016-06-24" @default.
• W2060494829 creator A5014204252 @default.
• W2060494829 creator A5021509802 @default.
• W2060494829 creator A5027951402 @default.
• W2060494829 creator A5030622546 @default.
• W2060494829 creator A5035851945 @default.
• W2060494829 creator A5038123418 @default.
• W2060494829 creator A5045181951 @default.
• W2060494829 creator A5058681104 @default.
• W2060494829 creator A5072336684 @default.
• W2060494829 date "1995-09-27" @default.
• W2060494829 modified "2023-10-17" @default.
• W2060494829 title "Enhancement ofin vitro tumor—cell transcellular migration by tumor—cell—secreted endothelial—cell—retraction factor" @default.
• W2060494829 cites W1670186976 @default.
• W2060494829 cites W1911310945 @default.
• W2060494829 cites W1969109645 @default.
• W2060494829 cites W1983763042 @default.
• W2060494829 cites W2003106060 @default.
• W2060494829 cites W2005934284 @default.
• W2060494829 cites W2009573241 @default.
• W2060494829 cites W2018163700 @default.
• W2060494829 cites W2020229432 @default.
• W2060494829 cites W2023247554 @default.
• W2060494829 cites W2026477506 @default.
• W2060494829 cites W2033269028 @default.
• W2060494829 cites W2037726220 @default.
• W2060494829 cites W2043863730 @default.
• W2060494829 cites W2058563741 @default.
• W2060494829 cites W2065678396 @default.
• W2060494829 cites W2069439683 @default.
• W2060494829 cites W2122070113 @default.
• W2060494829 cites W2150404521 @default.
• W2060494829 cites W2317105488 @default.
• W2060494829 cites W28084666 @default.
• W2060494829 cites W37222717 @default.
• W2060494829 cites W4211208200 @default.
• W2060494829 cites W4255042798 @default.
• W2060494829 cites W611533236 @default.
• W2060494829 doi "https://doi.org/10.1002/ijc.2910630120" @default.
• W2060494829 hasPubMedId "https://pubmed.ncbi.nlm.nih.gov/7558437" @default.
• W2060494829 hasPublicationYear "1995" @default.
• W2060494829 type Work @default.
• W2060494829 sameAs 2060494829 @default.
• W2060494829 citedByCount "26" @default.
• W2060494829 countsByYear W20604948292012 @default.
• W2060494829 countsByYear W20604948292013 @default.
• W2060494829 countsByYear W20604948292014 @default.
• W2060494829 countsByYear W20604948292016 @default.
• W2060494829 crossrefType "journal-article" @default.
• W2060494829 hasAuthorship W2060494829A5014204252 @default.
• W2060494829 hasAuthorship W2060494829A5021509802 @default.
• W2060494829 hasAuthorship W2060494829A5027951402 @default.
• W2060494829 hasAuthorship W2060494829A5030622546 @default.
• W2060494829 hasAuthorship W2060494829A5035851945 @default.
• W2060494829 hasAuthorship W2060494829A5038123418 @default.
• W2060494829 hasAuthorship W2060494829A5045181951 @default.
• W2060494829 hasAuthorship W2060494829A5058681104 @default.
• W2060494829 hasAuthorship W2060494829A5072336684 @default.
• W2060494829 hasConcept C123012128 @default.
• W2060494829 hasConcept C1491633281 @default.
• W2060494829 hasConcept C153911025 @default.
• W2060494829 hasConcept C176285220 @default.
• W2060494829 hasConcept C183521119 @default.
• W2060494829 hasConcept C185592680 @default.
• W2060494829 hasConcept C202751555 @default.
• W2060494829 hasConcept C54355233 @default.
• W2060494829 hasConcept C55493867 @default.
• W2060494829 hasConcept C79879829 @default.
• W2060494829 hasConcept C81885089 @default.
• W2060494829 hasConcept C86803240 @default.
• W2060494829 hasConcept C95444343 @default.
• W2060494829 hasConceptScore W2060494829C123012128 @default.
• W2060494829 hasConceptScore W2060494829C1491633281 @default.
• W2060494829 hasConceptScore W2060494829C153911025 @default.
• W2060494829 hasConceptScore W2060494829C176285220 @default.
• W2060494829 hasConceptScore W2060494829C183521119 @default.
• W2060494829 hasConceptScore W2060494829C185592680 @default.
• W2060494829 hasConceptScore W2060494829C202751555 @default.
• W2060494829 hasConceptScore W2060494829C54355233 @default.
• W2060494829 hasConceptScore W2060494829C55493867 @default.
• W2060494829 hasConceptScore W2060494829C79879829 @default.
• W2060494829 hasConceptScore W2060494829C81885089 @default.
• W2060494829 hasConceptScore W2060494829C86803240 @default.
• W2060494829 hasConceptScore W2060494829C95444343 @default.
• W2060494829 hasIssue "1" @default.
• W2060494829 hasLocation W20604948291 @default.
• W2060494829 hasLocation W20604948292 @default.
• W2060494829 hasOpenAccess W2060494829 @default.
• W2060494829 hasPrimaryLocation W20604948291 @default.
• W2060494829 hasRelatedWork W1609265143 @default.
• W2060494829 hasRelatedWork W2007129302 @default.
• W2060494829 hasRelatedWork W2047840115 @default.
• W2060494829 hasRelatedWork W2050262813 @default.
• W2060494829 hasRelatedWork W2181671393 @default.
• W2060494829 hasRelatedWork W2396435661 @default.
• W2060494829 hasRelatedWork W2736268164 @default.
• W2060494829 hasRelatedWork W2802411161 @default.

• next