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- W2060622897 abstract "Abstract Blood lymphocytes from patients before, during, and after radiation therapy were cultured with two concentrations of phytohemagglutinin, pokeweed mitogen, and concanavalin A, and incorporation of 3 H-labeled nucleosides into acid-precipitable material was measured on five consecutive days (2–6). Incorporation of [ 3 H]thymidine may be maximal on any one of the days measured (4,5, or 6) and very low on one or both of the others. [ 3 H]uridine incorporation on day 3 of culture is a more reliable index of response. The pattern of incorporation changes dramatically during the recovery period after radiation therapy. At 2–3 weeks after therapy, the early and late incorporations of nucleosides were both near normal. Two weeks later, however, the early response remained the same but the late incorporation had dropped to a very low level. Apparently, different circulating lymphocyte subpopulations were responding to the mitogen at these two intervals after radiation therapy." @default.
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- W2060622897 date "1976-07-01" @default.
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- W2060622897 title "The effect of radiation therapy on the kinetics of in vitro lymphocyte response to mitogens" @default.
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- W2060622897 doi "https://doi.org/10.1016/0090-1229(76)90056-8" @default.
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