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• W2060641168 abstract "International Journal of DermatologyVolume 30, Issue 10 p. 679-683 Aloe Vera Its Chemical and Therapeutic Properties Ronald M. Shelton MAJ, USAF, MC, Ronald M. Shelton MAJ, USAF, MC From the Department of Dermatology, Brooke Army Medical Center, Fort Sam Houston, San Antonio, Texas.Search for more papers by this author Ronald M. Shelton MAJ, USAF, MC, Ronald M. Shelton MAJ, USAF, MC From the Department of Dermatology, Brooke Army Medical Center, Fort Sam Houston, San Antonio, Texas.Search for more papers by this author First published: October 1991 https://doi.org/10.1111/j.1365-4362.1991.tb02607.xCitations: 174 The opinions or assertions herein are the private of the author and are not to be construed as reflecting the views of the Department of the Army or the Department of Defense. AboutPDF ToolsRequest permissionExport citationAdd to favoritesTrack citation ShareShare Give accessShare full text accessShare full-text accessPlease review our Terms and Conditions of Use and check box below to share full-text version of article.I have read and accept the Wiley Online Library Terms and Conditions of UseShareable LinkUse the link below to share a full-text version of this article with your friends and colleagues. Learn more.Copy URL References 1 Coats BC, Ahola R. Aloe Vera the Silent Healer. A Modern Study of Aloe Vera. Dallas : Bill C. Coats, 1979: 1– 288. 2 Cole HN, Chen KK. Aloe vera in oriental dermatology. Arch Dermatol Syphilol. 1943; 47: 250. 3 Gottlieb K. Aloe Vera Heals. The Scientific Facts. Denver , CO : Royal Publications, 1980: 1– 31. 4 Klein AD, Penneys N. Aloe vera. J Am Acad Dermatol. 1988; 18: 714– 720. 5 JEF Reynolds, ed. Martindale—The Extra Pharmacopeia. London : The Pharmaceutical Press, 1989: 1074– 1075. 6 S Budavari, ed. The Merck Index. An Encyclopedia of Chemicals, Drugs, and Biologicals. Rahway , NJ : Merck and Co., 1989: 51. 7 Tyler VE, Brady LR, Robbers JE. Pharmacognosy. Philadelphia : Lea and Febiger, 1976: 81– 83. 8 Grindlay D, Reynolds T. The aloe vera phenomenon: A review of the properties and modern uses of the leaf parenchyma gel. J Ethnopharmacol. 1986; 16: 117– 151. 9 Morton JF. Folk uses and commercial exploitation of aloe leaf pulp. Econ Bot. 1961; 115: 311– 319. 10 Flagg J. Aloe vera gel in dermatological preparations. Am Perfum Cosmet. 1959; 74: 27– 29. 11 Durand M, Paris R. Les aloes: II. Etude chromatographique des derives anthraceniques de divers aloes frais. Ann Pharm Fr. 1960; 18: 846– 852. 12 Gjerstad G. Chemical studies of aloe vera juice: I. Amino acid analysis. Adv Front PI Sci. 1971; 28: 311– 315. 13 Rowe TD, Parks LM. A phytochemical study of aloe vera leaf. J Am Pharm Assoc. 1941; 30: 262– 265. 14 Robson MC, Heggers JP, Hagstrom WJ. Myth, magic, witchcraft or fact? Aloe vera revisited. J Burn Care Rehabil. 1982; 3: 157– 162. 15 Danhof IE, McAnally BH. Stabilized aloe vera: Effect on human skin cells. Drug Cosmet Ind. 1983; 133: 52– 106. 16 Davis RH, Maro NP. Aloe vera and gibberellin: Anti-inflammatory activity in diabetes. J Am Podiatr Med Assoc. 1989; 79: 24– 26. 17 Benigni R. Substances with antibiotic action contained in anthraquinonic drugs. Chem Ab. 1950; 44: 11036. 18 Hanley DC, Solomon WAB, Saffron B, et al. The evaluation of natural substances in the treatment of adjuvant arthritis. J Am Podiatr Med Assoc. 1982; 72: 275– 284. 19 Fujita K., Teradaira R. Bradykininase activity of aloe extract. Biochem Pharmacol. 1976; 25: 205. 20 Fujita K, Shasike I, Teradaira R, et al. Properties of a carboxy-peptidase from aloe. Biochem Pharmacol. 1979; 28: 1261– 1262. 21 Cera LM, Heggers JP, Robson MC, et al. The therapeutic efficacy of aloe vera cream (dermaide aloe) in thermal injuries: Two case reports. J Am Anim Hosp Assoc. 1980; 16: 768– 772. 22 Cera LM, Heggers JP, Hagstrom WJ, et al. Therapeutic protocol for thermally injured animals and its successful use in an extensively burned rhesus monkey. J Am Anim Hosp Assoc. 1982; 18: 633– 638. 23 Davis RH, Rosenthal KY, Cesario LR, et al. Processed aloe vera administered topically inhibits inflammation. J Am Podiatr Med Assoc. 1989; 79: 395– 397. 24 Davis RH, Leitner MG, Russo JM, et al. Anti-inflammatory activity of aloe vera against a spectrum of irritants. J Am Podiatr Med Assoc. 1989; 79: 263– 276. 25 Winters WD, Benavides R, Clouse WJ. Effects of aloe extracts on human normal and tumor cells in vitro. Econ Bot. 1981; 35: 89– 95. 26 Penneys NS. Inhibition of arachidonic acid oxidation in vitro by vehicle components. Acta Derm Venereol. 1982; 62: 59– 61. 27 Ashley FL, O'Loughlin BJ, Peterson R, et al. The use of aloe vera in the treatment of thermal and irradiation burns in laboratory animals and humans. Plast Reconstr Surg. 1957; 20: 383– 396. 28 Kupchan SM, Karim A. Tumor inhibitors: 114. Aloe emodin. Antileukemic principle isolated from rhamnus frangula 1. Lloydia. 1976; 39: 223– 224. 29 Gottshall RY, Jennings JC, Weller LE, et al. Antibacterial substances in seed plants active against tubercle bacilli. Am Rev Tuberc. 1950; 62: 475– 480. 30 Bruce WG. Investigations of antibacterial activity in the aloe. S Afr Med J. 1967; 41: 984. 31 Lorenzetti LJ, Salisbury R, Beal JL, et al. Bacteriostatic property of aloe vera. J Pharm Sci. 1964; 53: 1287. 32 Zimmerman ER, Simms R. Antibacterial and Antifungal In-vitro Properties of Aloe Vera. Dallas , TX : Baylor University College of Dentistry, Microbiology Laboratory, March 1969 (unpublished data on file). 33 Collins CE, Collins C. Roentgen dermatitis treated with fresh whole leaf of aloe vera. Am J Roentgenol. 1935; 33: 396. 34 Wright CS. Aloe vera in treatment of roentgen ulcers and telangiectasis. JAMA. 1936; 106: 1363– 1364. 35 Loveman AB. Leaf of aloe vera in treatment of roentgen ray ulcers. Arch Dermatol Syphilol. 1937; 36: 838– 843. 36 Crewe JE. The external use of aloes. Minn Med. 1937; 20: 670– 673. 37 Mandeville FB. Aloe vera in the treatment of radiation ulcers of mucous membranes. Radiology. 1939; 32: 598– 599. 38 Crewe JE. Aloes in the treatment of burns and scalds. Minn Med. 1939; 2: 538– 539. 39 Rowe TD, Lovell BK, Parks LM. Further observations on the use of aloe vera leaf in the treatment of third degree x-ray reactions. J Am Pharm Assoc. 1941; 30: 265– 269. 40 Tchou MT. Aloe vera (jelly leeks). Arch Dermatol Syphilol. 1943; 47: 249. 41 Barnes TC. The healing action of extracts of aloe vera leaf on abrasions of human skin. Am J Bot. 1947; 34: 597. 42 Lushbaugh CC, Hale DB. Experimental acute radiodermatitis following beta irradiation: V. Histopathological study of the mode of action of therapy with aloe vera. Cancer. 1953; 6: 690– 697. 43 Blitz J, Smith JW, Gerard JR. Aloe vera gel in peptic ulcer therapy: Preliminary report. J Am Osteopath Assoc. 1963; 63: 731– 735. 44 Sjostrom B, Weatherly-White RCA, Paton BC. Experimental studies in cold injury. J Surg Res. 1964; 4: 12– 16. 45 Raine TJ, London MD, Goluch K, et al. Antiprostaglandins and antithromboxanes for treatment of frostbite. Surg Forum. 1980; 31: 557– 559. 46 McCauley RL, King DN, Robson MC, et al. Frostbite injuries: A rational approach based on the pathophysiology. J Trauma. 1983; 23: 143– 147. 47 Zawacki BE. Reversal of capillary stasis and prevention of burns. Ann Surg. 1974; 180: 98– 102. 48 Zawahry ME, Hegazy MR, Helal M. Use of aloe in treating leg ulcers and dermatoses. Int J Dermatol. 1973; 12: 68– 73. 49 Heggers JP, Loy G, Robson MC. Histological demonstration of prostaglandins and thromboxanes in burned tissue. J Surg Res. 1979; 28: 110– 117. 50 Rodriguez-Bigas M, Cruz NI, Suarez A. Comparative evaluation of aloe vera in the management of burn wounds in guinea pigs. Plast Reconstr Surg. 1988; 81: 386– 389. 51 Kaufman T, Kalderon N, Ullman Y, et al. Aloe vera gel hindered wound healing of experimental second-degree burns: A quantitative controlled study. J Burn Care Rehabil. 1988; 9: 156. 52 Davis RH, Kabbani JM, Marno NP. Wound healing and anti-inflammatory activity of aloe vera. Proc Pa Acad Sci. 1986; 60: 79. 53 Davis RH, Agnew PS, Shapiro E. Antiarthritic activity of anthaquinones found in aloe for podiatric medicine. J Am Podiatr Med Assoc. 1986; 76: 61– 62. 54 Watcher MA, Wheel RG. The role of topical agents in the healing of full-thickness wounds. J Dermatol Surg Oncol. 1989; 15: 1188– 1195. 55 Fulton JE. The stimulation of post dermabrasion wound healing with stabilized aloe vera gel-polyethylene oxide dressing. J Dermatol Surg Oncol. 1990; 16: 460– 467. 56 Davis RH, Leitner MG, Russo JM. Topical anti-inflammatory activity of aloe vera as measured by ear swelling. J Am Podiatr Med Assoc. 1987; 77: 610– 612. 57 Heeth A. The overselling of aloe vera. FDA Consum. 1981; 15: 27– 29. 58 Shoji A. Contact dermatitis to aloe arborescens. Contact Dermatitis. 1982; 8: 164– 167. 59 Nakamura T, Kotajima S. Contact dermatitis from aloe arborescens. Contact Dermatitis. 1984; 11: 51. 60 Hogan DJ. Widespread dermatitis after topical treatment of chronic leg ulcers and stasis dermatitis. Can Med Assoc J. 1988; 138: 336– 338. 61 Morrow DM, Rappaport MJ, Strick RA. Hypersensitivity to aloe. Arch Dermatol. 1980; 116: 1064– 1065. Citing Literature Volume30, Issue10October 1991Pages 679-683 ReferencesRelatedInformation" @default.
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