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- W2060679900 abstract "Imprinted genes are monoallelically expressed in a parent-of-origin manner and were previously identified in both marsupials and eutherians, but not in monotremes. Phylogenetic comparison of imprinted domains is a powerful tool for investigating the molecular and adaptive evolution of this unique gene regulatory mechanism. Herein, we report that multiple transcripts of Dlk1 (Delta, Drosophila, Homolog-like 1) are expressed in the opossum, but none are imprinted. Thus, we provide the first example of a reciprocally imprinted gene domain in which imprinting evolved in a common ancestor to eutherian rather than therian mammals. Moreover, the reciprocally imprinted Meg3 (Maternally Expressed Gene 3), found downstream of Dlk1 in eutherian mammals, is absent in the opossum. We propose that the Meg3 sequence integrated into the eutherian Dlk1 domain via a LINE-1 element and that Dlk1 became imprinted in eutherian mammals only after this downstream integration. These findings clearly demonstrate that imprinted genes did not all evolve before the divergence of marsupials and eutherians." @default.
- W2060679900 created "2016-06-24" @default.
- W2060679900 creator A5007126253 @default.
- W2060679900 creator A5017963958 @default.
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- W2060679900 date "2006-02-01" @default.
- W2060679900 modified "2023-10-18" @default.
- W2060679900 title "Comparative phylogenetic analysis reveals multiple non-imprinted isoforms of opossum Dlk1" @default.
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- W2060679900 cites W1804006179 @default.
- W2060679900 cites W1945591912 @default.
- W2060679900 cites W1964789204 @default.
- W2060679900 cites W1967589170 @default.
- W2060679900 cites W1971560725 @default.
- W2060679900 cites W1989292359 @default.
- W2060679900 cites W1989981870 @default.
- W2060679900 cites W1999579544 @default.
- W2060679900 cites W2004780659 @default.
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- W2060679900 cites W2010914889 @default.
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- W2060679900 cites W2018813217 @default.
- W2060679900 cites W2018947009 @default.
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- W2060679900 doi "https://doi.org/10.1007/s00335-005-0116-x" @default.
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