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• W2060691165 abstract "In human blood, the PET radiotracer [18F]CPFPX (1) is metabolized to numerous metabolites, one (M1) being the most prominent in plasma 30 min p.i. Because the mass of injected tracer is ≤5 nmol, concentrations in plasma are too low to analyze. Human liver microsomes generate main metabolites having HPLC retention times identical to those in plasma. HPLC−MS tentatively identified M1 as 2. Synthesis of 2 and identical HPLC−MS spectra of 2 and M1 confirmed that assignment." @default.
• W2060691165 created "2016-06-24" @default.
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• W2060691165 date "2009-09-02" @default.
• W2060691165 modified "2023-10-16" @default.
• W2060691165 title "Synthesis of the Main Metabolite in Human Blood of the A₁ Adenosine Receptor Ligand [¹⁸F]CPFPX" @default.
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• W2060691165 doi "https://doi.org/10.1021/ol900169f" @default.
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